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Burning Rock Reports Third Quarter 2024 Financial Results

GUANGZHOU, China, Dec. 03, 2024 (GLOBE NEWSWIRE) — Burning Rock Biotech Limited (NASDAQ: BNR, the “Company” or “Burning Rock”), a company focused on the application of next generation sequencing (NGS) technology in the field of precision oncology, today reported financial results for the three months ended September 30, 2024.

Recent Business Updates

  • Therapy Selection
    • Presented study results at the 2024 World Conference on Lung Cancer in September 2024. “Neoadjuvant sintilimab plus chemotherapy could be an optional treatment modality in selected EGFR-mutant NSCLC” and “Distinct Genomic and Immune Microenvironment Features of Solid or Micropapillary Predominant Subtype in Stage I Lung Adenocarcinomas”.
    • Signed a strategic cooperation agreement with MGI Tech Co., Ltd in October 2024, aiming to fully complement each other’s platform and technological advantages to further promote the clinical application progress and global business of precision oncology.
  • Pharma Services
    • The companion diagnostic (CDx) for EGFR exon 20 insertion mutation (exon20ins) for sunvozertinib, developed through the collaboration of Burning Rock and Dizal, has been approved by the National Medical Products Administration (NMPA) of China, which marks the first co-developed NGS-based CDx for lung cancer approved by NMPA since the release of the CDx guideline in China.

Third Quarter 2024 Financial Results

Total revenues were RMB128.6 million (US$18.3 million) for the three months ended September 30, 2024, representing a 0.8% increase from RMB127.6 million for the same period in 2023, the increased revenue of in-hospital business was offset by the decrease of central-lab business, as we transition from central-lab to more in-hospital based testing.

  • Revenue generated from in-hospital business was RMB63.8 million (US$9.1 million) for the three months ended September 30, 2024, representing a 17.0% increase from RMB54.5 million for the same period in 2023, driven by an increase in sales volume.
  • Revenue generated from central laboratory business was RMB40.0 million (US$5.7 million) for the three months ended September 30, 2024, representing a 25.2% decrease from RMB53.5 million for the same period in 2023, primarily attributable to a decrease in the number of tests, as we continued our transition towards in-hospital testing.
  • Revenue generated from pharma research and development services was RMB24.9 million (US$3.5 million) for the three months ended September 30, 2024, representing a 27.1% increase from RMB19.6 million for the same period in 2023, primarily attributable to an increased development and testing services performed for our pharma customers.

Cost of revenues was RMB36.8 million (US$5.2 million) for the three months ended September 30, 2024, representing an 11.6% decrease from RMB41.6 million for the same period in 2023, primarily due to (i) a decrease in cost of central laboratory business, which was in line with the decrease in revenue generated from this business; (ii) a decrease in amortization expense for all kinds of business; and (iii) the receipt of a government grant for Guangzhou headquarters building.

Gross profit was RMB91.8 million (US$13.1 million) for the three months ended September 30, 2024, representing a 6.9% increase from RMB85.9 million for the same period in 2023. Gross margin was 71.4% for the three months ended September 30, 2024, compared to 67.4% for the same period in 2023. By channel, gross margin of central laboratory business was 83.2% for the three months ended September 30, 2024, compared to 77.6% during the same period in 2023, primarily due to the decreased depreciation and rental cost in relation to our laboratory of Guangzhou headquarters; gross margin of in-hospital business was 73.0% for the three months ended September 30, 2024, compared to 65.1% during the same period in 2023, primarily due to the same reason; gross margin of pharma research and development services was 48.2% for the three months ended September 30, 2024, compared to 45.8% during the same period of 2023.

Non-GAAP gross profit, which excludes depreciation and amortization expenses, was RMB97.8 million (US$13.9million) for the three months ended September 30, 2024, representing a 2.8% increase from RMB95.1 million for the same period in 2023. Non-GAAP gross margin was 76.0% for the three months ended September 30, 2024, compared to 74.5% for the same period in 2023.

Operating expenses were RMB130.4 million (US$18.6 million) for the three months ended September 30, 2024, representing a 50.7% decrease from RMB264.7 million for the same period in 2023. The decrease was primarily driven by decreases in amortized expense on share-based compensation, budget control measures and headcount reduction to improve the Company’s operating efficiency.

  • Research and development expenses were RMB49.2 million (US$7.0 million) for the three months ended September 30, 2024, representing a 41.3% decrease from RMB83.7 million for the same period in 2023, primarily due to (i) a decrease in staff cost resulted from the reorganization of our research and development department to improve operating efficiency; (ii) a decrease in the expenditure for research projects; (iii) a decrease in amortized expense on share-based compensation; and (iv) a decrease in amortized expenses for office building decoration.
  • Selling and marketing expenses were RMB48.4 million (US$6.9 million) for the three months ended September 30, 2024, representing a 22.3% decrease from RMB62.3 million for the same period in 2023, primarily due to (i) a decrease in staff cost resulted from the reorganization of the sales department and improvement in operating efficiency; (ii) a decrease in conference fee; and (iii) a decrease in entertainment expense.
  • General and administrative expenses were RMB32.9 million (US$4.7 million) for the three months ended September 30, 2024, representing a 72.3% decrease from RMB118.7 million for the same period in 2023, primarily due to (i) a decrease in amortized expense on share-based compensation; (ii) a decrease in amortized expenses for office building decoration; (iii) a decrease in operating lease; and (iv) a decrease in general and administrative personnel’s staff cost.

Net loss was RMB35.7 million (US$5.10 million) for the three months ended September 30, 2024, compared to RMB175.0 million for the same period in 2023.

Cash, cash equivalents, restricted cash and short-term investments were RMB498.2 million (US$71.0 million) as of September 30, 2024.

About Burning Rock

Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.

For more information about Burning Rock, please visit: ir.brbiotech.com.

Safe Harbor Statement

This press release contains forward-looking statements. These statements constitute “forward-looking” statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates,” “target,” “confident” and similar statements. Burning Rock may also make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Burning Rock’s beliefs and expectations, are forward-looking statements. Such statements are based upon management’s current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond Burning Rock’s control. Forward-looking statements involve risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. All information provided in this press release is as of the date of this press release, and Burning Rock does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.

Non-GAAP Measures

In evaluating the business, the Company considers and uses non-GAAP measures, such as non-GAAP gross profit and non-GAAP gross margin, as supplemental measures to review and assess operating performance. The presentation of these non-GAAP financial measures is not intended to be considered in isolation or as a substitute for the financial information prepared and presented in accordance with accounting principles generally accepted in the United States of America (“U.S. GAAP”). The company defines non-GAAP gross profit as gross profit excluding depreciation and amortization. The company defines non-GAAP gross margin as gross margin excluding depreciation and amortization.

The company presents these non-GAAP financial measures because they are used by management to evaluate operating performance and formulate business plans. The company believe non-GAAP gross profit and non-GAAP gross margin excluding non-cash impact of depreciation and amortization reflect the company’s ongoing business operations in a manner that allows more meaningful period-to-period comparisons.

Contact: IR@brbiotech.com

Selected Operating Data

 As of
 September
30, 2023
December
31, 2023
March 31,
2024
June 30,
2024
September
30, 2024
In-hospital Channel:     
Pipeline partner hospitals(1)2928282930
Contracted partner hospitals(2)5559595961
Total number of partner hospitals 84 87 87 8891
(1) Refers to hospitals that are in the process of establishing in-hospital laboratories, laboratory equipment procurement or installation, staff training or pilot testing using the Company’s products.
(2) Refers to hospitals that have entered into contracts to purchase the Company’s products for use on a recurring basis in their respective in-hospital laboratories the Company helped them establish. Kit revenue is generated from contracted hospitals.
 

Selected Financial Data

 
 For the three months ended 
Revenues

September
30, 2023
December
31, 2023
March 31,
2024
June 30,
2024
September
30, 2024
 
 (RMB in thousands)
Central laboratory channel53,48151,28847,61448,77339,984 
In-hospital channel54,49628,809 57,38759,87263,769 
Pharma research and development channel19,58940,98820,62226,88824,891 
Total revenues127,566 121,085 125,623 135,533 128,644  

 For the three months ended 
Gross profit

September
30, 2023
December
31, 2023
March 31,
2024
June 30,
2024
September
30, 2024
 
 (RMB in thousands)
Central laboratory channel41,48741,88637,00238,42433,262 
In-hospital channel35,45912,91039,19244,05846,580 
Pharma research and development channel8,97423,3179,50012,95612,004 
Total gross profit85,920    78,113 85,694 95,438 91,846  

 For the three months ended 
Share-based compensation expenses

September
30, 2023
December
31, 2023
March 31,
2024
June 30,
2024
September
30, 2024
 
 (RMB in thousands)
Cost of revenues680654596464289 
Research and development expenses12,16112,40112,28712,0083,180 
Selling and marketing expenses2,8481,8165081,2321,917 
General and administrative expenses57,70456,47255,99054,4074,732 
Total share-based compensation expenses 73,393 71,343 69,381 68,111 10,118  
       

Burning Rock Biotech Limited
Unaudited Condensed Statements of Comprehensive Loss
(in thousands, except for number of shares and per share data)
 For the three months ended
 September
30, 2023
 December
31,2023
 March 31,
2024
 June 30,
2024
 September
30, 2024
 September
30, 2024
 
 RMB RMB RMB RMB RMB US$ 
Revenues127,566  121,085  125,623  135,533  128,644  18,331   
Cost of revenues(41,646)(42,972)(39,929 )(40,095 )(36,798)(5,243) 
Gross profit 85,920  78,113  85,694  95,438  91,846  13,088   
Operating expenses:       
              
Research and development expenses(83,701)(73,119)(65,985)(64,952)(49,150)(7,004) 
Selling and marketing expenses(62,310)(49,785)(46,856)(48,907)(48,411)(6,899) 
General and administrative expenses(118,724)(121,533)(98,681)(92,794)(32,874)(4,685) 
Total operating expenses   (264,735)   (244,437)(211,522 )(206,653 )(130,435)(18,588) 
Loss from operations (178,815)(166,324)(125,828 )(111,215)(38,589)(5,500) 
Interest income4,018 5,539 4,038 3,187 3,173 452  
Other income (expense), net(157)160 434 (82)1   
Foreign exchange (loss) gain, net423 (517)(13)262 (129)(18) 
Loss before income tax (174,531)(161,142)(121,369 )(107,848 )(35,544)(5,066) 
Income tax expenses      (450)     (1,071)(180)    (190)(201)(29) 
Net loss   (174,981)   (162,213)(121,549 )(108,038 )(35,745)(5,095) 
Net loss attributable to Burning Rock Biotech Limited’s shareholders(174,981)(162,213)(121,549 )(108,038)(35,745)(5,095) 
Net loss attributable to ordinary shareholders(174,981)(162,213)(121,549 )(108,038)(35,745)(5,095) 
Loss per share for class A and class B ordinary shares:       
Class A ordinary shares – basic and diluted(1.71)(1.58)(1.19 )(1.05 )(0.35) (0.05) 
Class B ordinary shares – basic and diluted (1.71)(1.58)(1.19 )(1.05 ) (0.35) (0.05) 
Weighted average shares outstanding used in loss per share computation:        
Class A ordinary shares – basic and diluted85,000,869 85,071,360 85,219,188 85,271,858 85,902,670 85,902,670  
Class B ordinary shares – basic and diluted17,324,848 17,324,848 17,324,848 17,324,848 17,324,848 17,324,848  
Other comprehensive income (loss), net of tax of nil:       
Foreign currency translation adjustments(1,955)(3,026)590 940 (4,054)(578) 
Total comprehensive loss (176,936 )(165,239)(120,959 )(107,098)(39,799)(5,673) 
Total comprehensive loss attributable to Burning Rock Biotech Limited’s shareholders (176,936)(165,239)(120,959 )(107,098 )(39,799)(5,673) 
              

Burning Rock Biotech Limited
Unaudited Condensed Statements of Comprehensive Loss
(in thousands, except for number of shares and per share data)
 For the nine months ended
 September 30,
2023
 September 30,
2024
 September 30,
2024
 
 RMBRMBUS$
Revenues416,350  389,800  55,546  
Cost of revenues(131,236)(116,822)(16,648)
Gross profit285,114  272,978  38,898  
Operating expenses:   
Research and development expenses(273,897)(180,087)(25,662)
Selling and marketing expenses(197,926)(144,174)(20,545)
General and administrative expenses(316,288)(224,349)(31,969)
Total operating expenses(788,111)(548,610)(78,176)
Loss from operations (502,997)(275,632)(39,278)
Interest income12,417 10,398 1,482 
Other income, net324 353 50 
Foreign exchange gain, net97 120 17 
Loss before income tax(490,159)(264,761)(37,729)
Income tax expenses(1,317)(571)(81)
Net loss(491,476)(265,332)(37,810)
Net loss attributable to Burning Rock Biotech Limited’s shareholders(491,476)(265,332)(37,810)
Net loss attributable to ordinary shareholders(491,476)(265,332)(37,810)
Loss per share for class A and class B ordinary shares:   
Class A ordinary shares – basic and diluted(4.80)(2.58)(0.37)
Class B ordinary shares – basic and diluted(4.80)(2.58)(0.37)
Weighted average shares outstanding used in loss per share computation:    
Class A ordinary shares – basic and diluted85,070,921 85,467,131 85,467,131 
Class B ordinary shares – basic and diluted17,324,848 17,324,848 17,324,848 
Other comprehensive income (loss), net of tax of nil:   
Foreign currency translation adjustments7,215 (2,524)(360)
Total comprehensive loss(484,261)(267,856)(38,170)
Total comprehensive loss attributable to Burning Rock Biotech Limited’s shareholders(484,261)(267,856)(38,170)
       

 
Burning Rock Biotech Limited
Unaudited Condensed Consolidated Balance Sheets
(In thousands)
 As of
 December 31,
2023
September 30,
2024
September 30,
2024
 RMB RMBUS$
ASSETS   
Current assets:   
Cash and cash equivalents615,096497,96970,960
Restricted cash12027840
Accounts receivable, net126,858166,49123,725
Contract assets, net22,74817,7502,529
Inventories, net69,02066,4449,468
Prepayments and other current assets, net50,25430,6234,364
Convertible note receivable5,320758
Total current assets 884,096 784,875 111,844

Non-current assets:

   
Equity method investment33724335
Convertible note receivable5,320
Property and equipment, net131,91290,13912,845
Operating right-of-use assets12,28499,30114,150
Intangible assets, net96452575
Other non-current assets5,0889,7221,385
Total non-current assets 155,905 199,930 28,490
TOTAL ASSETS   1,040,001 984,805 140,334
    

Burning Rock Biotech Limited
Unaudited Condensed Consolidated Balance Sheets (Continued)
(in thousands)
 As of
 December 31,
2023
 September 30,
2024
 September 30,
2024
 
 RMB RMBUS$
LIABILITIES AND SHAREHOLDERS’ EQUITY   
Current liabilities:   
Accounts payable18,061 25,213 3,593 
Deferred revenue130,537 110,748 15,781 
Accrued liabilities and other current liabilities104,935 94,110 13,411 
Customer deposits1,197 567 81 
Current portion of operating lease liabilities8,634 27,842 3,967 
Total current liabilities 263,364   258,480   36,833  
Non-current liabilities:   
Non-current portion of operating lease liabilities3,690 73,055 10,410 
Other non-current liabilities4,537 5,104 728 
Total non-current liabilities 8,227   78,159   11,138  
TOTAL LIABILITIES 271,591   336,639   47,971  

Shareholders’ equity:

   
Class A ordinary shares116 118 17 
Class B ordinary shares21 21 3 
Additional paid-in capital4,849,337 4,996,947 712,059 
Treasury stock(65,896)(65,896)(9,390)
Accumulated deficits(3,853,635)(4,118,967)(586,948)
Accumulated other comprehensive loss(161,533)(164,057)(23,378)
Total shareholders’ equity768,410  648,166  92,363  
TOTAL LIABILITIES AND SHAREHOLDERS’ EQUITY1,040,001  984,805  140,334  
       

Burning Rock Biotech Limited
Unaudited Condensed Statements of Cash Flows
(in thousands)
 For the three months ended
 September
30, 2023
September
30, 2024
September
30,
2024
 RMBRMBUS$
Net cash used in operating activities(47,417)(30,278)(4,315)
Net cash used in investing activities(1,985)(987)(141)
Net cash (used in)/generated from financing activities(45,888)2  
Effect of exchange rate on cash, cash equivalents and restricted cash(1,239)(3,537)(503)
Net decrease in cash, cash equivalents and restricted cash (96,529)(34,800)(4,959)
Cash, cash equivalents and restricted cash at the beginning of period733,278 533,047 75,959 
Cash, cash equivalents and restricted cash at the end of period636,749  498,247  71,000  
    

 For the nine months ended
 September
30, 2023
September
30, 2024
September
30, 2024
 RMBRMBUS$
Net cash used in operating activities(239,764)(111,323)(15,863)
Net cash used in investing activities(8,972)(3,600)(513)
Net cash (used in)/generated from financing activities(46,923)2  
Effect of exchange rate on cash, cash equivalents and restricted cash7,140 (2,048)(292)
Net decrease in cash, cash equivalents and restricted cash (288,519)(116,969)(16,668)
Cash, cash equivalents and restricted cash at the beginning of period925,268 615,216 87,668 
Cash, cash equivalents and restricted cash at the end of period636,749  498,247  71,000  
    

Burning Rock Biotech Limited
Reconciliations of GAAP and Non-GAAP Results

  For the three months ended
 September
30, 2023
 December
31, 2023
 March 31,
2024
 June 30,
2024
 September
30, 2024
 
  (RMB in thousands)
Gross profit:

  
Central laboratory channel41,487 41,886 37,002 38,424 33,262 
In-hospital channel35,459 12,910 39,192 44,058 46,580 
Pharma research and development channel8,974 23,317 9,500 12,956 12,004 
Total gross profit

85,920 78,113 85,694 95,438  91,846  
Add: depreciation and amortization:      
Central laboratory channel2,550 2,414 1,919 1,226 1,277 
In-hospital channel2,751 2,728 1,524 824 798 
Pharma research and development channel3,863 3,808 3,856 4,417 3,846 
Total depreciation and amortization included in cost of revenues

9,164  8,950  7,299  6,467  5,921  
Non-GAAP gross profit:     
Central laboratory channel44,037 44,300 38,921 39,650 34,539 
In-hospital channel38,210 15,638 40,716 44,882 47,378 
Pharma research and development channel12,837 27,125 13,356 17,373 15,850 
Total non-GAAP gross profit95,084 87,063 92,993  101,905 97,767 
Non-GAAP gross margin:     
Central laboratory channel82.3%86.4%81.7%81.3%86.4%
In-hospital channel70.1%54.3%70.9%75.0%74.3%
Pharma research and development channel65.5%66.2%64.8%64.6%63.7%
Total non-GAAP gross margin74.5%71.9%74.0%75.2%76.0%

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