Demonstrated meaningful overall anemia responses across all patient subgroups, regardless of baseline transfusion status
Anemia response was seen independent of concomitant JAK inhibitor therapy useWATERTOWN, Mass., Dec. 06, 2025 (GLOBE NEWSWIRE) — Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from serious hematologic diseases, today presented positive initial data from the RALLY-MF Phase 2 trial of DISC-0974 in anemia of MF at the ASH Annual Meeting in Orlando, FL. The data demonstrated that treatment with DISC-0974 resulted in substantial reductions in hepcidin and increases in iron levels translating to positive impact on clinically meaningful measures of anemia across a broad range of patient...
Arvinas Presents Preclinical Data Supporting Mechanistic Synergies and Enhanced Antitumor Activity with the Combination of ARV-393 and Glofitamab at the 2025 American Society of Hematology Annual Meeting and Exposition
Written by Customer Service on . Posted in Public Companies.
– Data support initiation of a combination cohort in the ongoing Phase 1 clinical trial to evaluate ARV-393 plus glofitamab as a chemotherapy-free combination approach in diffuse large B-cell lymphoma (DLBCL); initiation expected in 2026 –
NEW HAVEN, Conn., Dec. 06, 2025 (GLOBE NEWSWIRE) — Arvinas, Inc. (Nasdaq: ARVN), a clinical-stage biotechnology company creating a new class of drugs based on targeted protein degradation, today announced preclinical data for ARV-393, a PROTAC BCL6 degrader, in combination with glofitamab, a CD20×CD3 bispecific antibody, presented in a poster at the 67th American Society of Hematology (ASH®) Annual Meeting and Exposition, held December 6–9, 2025, in Orlando, Florida. In a humanized high-grade B-cell lymphoma (HGBCL) cell line–derived xenograft (CDX) model, the combination of ARV-393 and glofitamab...
Scatec starts commercial operation at Grootfontein solar power plant in South Africa
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Oslo/Cape Town, 06 December 2025: Scatec ASA, a leading renewable energy provider, has started commercial operation of the 273 MW Grootfontein solar power plant in South Africa, which will generate predictable revenues from a 20-year power purchase agreement (PPA).
“We are proud to commence commercial operations at Grootfontein, reinforcing our strong track record in South Africa. This project builds on our commitment to deliver clean, reliable energy while creating long-term value for local communities and partners. We thank our stakeholders for their continued collaboration and look forward to continuing our support of the energy transition in South Africa,” says Scatec CEO, Terje Pilskog.
“Bringing the Grootfontein plant into operation is an important milestone for Scatec and our partners. As our first project in the Western Cape, and...
Toripalimab Presents Long-Term Survival Benefits as 1st-line Treatment for Advanced Nasopharyngeal Carcinoma and Esophageal Squamous Cell Carcinoma Patients
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Long-term OS follow-up analysis of JUPITER-02 demonstrates significantly better and clinically meaningful improvement with toripalimab plus chemotherapy as 1st-line treatment for R/M NPC, achieving mOS of 64.8 months and a 5-year OS rate of 52.3%.
Torpalimab plus chemotherapy has been approved in over 40 countries, representing the new standard of care for the 1st line treatment of R/M NPC.
The final OS analysis of JUPITER-06 confirms the sustained survival benefit with toripalimab plus chemotherapy in advanced ESCC, showing a mOS of 17.7 months and a 3-year OS rate of 29.7%.
Results from JUPITER-02 and JUPITER-06 were orally presented at ESMO Asia 2025.SHANGHAI, Dec. 05, 2025 (GLOBE NEWSWIRE) — Shanghai Junshi Biosciences Co., Ltd (Junshi Biosciences, HKEX: 1877; SSE: 688180), a leading innovation-driven biopharmaceutical company...
ORIC® Pharmaceuticals Presents Potential Best-in-Class Profile for Enozertinib with Robust Systemic and CNS Activity in 1L and 2L NSCLC Patients with EGFR Exon 20 Mutations at the ESMO Asia Congress 2025
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Highly differentiated 1L preliminary systemic activity of 67% ORR and 100% intracranial ORR (by BICR-RANO), including in patients with active brain metastases
45% ORR in 2L patients exceeds competitor benchmarks
Competitive safety profile, with no significant off-target toxicity and manageable on-target toxicity, resulting in low discontinuation rate
Enrollment and follow-up continue in 1L patients at selected dose of 80 mg once daily, with next update expected mid-2026 ahead of initiation of potential Phase 3 trial
Company to host a conference call and webcast on Saturday, December 6, 2025, at 8:00 pm ET
SOUTH SAN FRANCISCO, Calif. and SAN DIEGO, Dec. 05, 2025 (GLOBE NEWSWIRE) — ORIC Pharmaceuticals, Inc. (Nasdaq: ORIC), a clinical stage oncology company focused on developing treatments that address mechanisms of therapeutic...
Copper Quest Closes $1,927,000 Private Placement
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// Not for distribution to the United States newswire services or for dissemination in the United States //
VANCOUVER, British Columbia, Dec. 05, 2025 (GLOBE NEWSWIRE) — Copper Quest Exploration Inc. (CSE: CQX; FRA: 3MX) (“Copper Quest” or the “Company”) is pleased to announce that, further to its news release dated December 1, 2025, it has issued an aggregate of 10,142,104 flow-through shares of the Company (the “FT Shares“, and each, a “FT Share“) at a price of $0.19 per FT Share for aggregate gross proceeds of $1,927,000 in connection with its previously announced fully subscribed non-brokered private placement (the “Private Placement“).
Each FT Share constitutes a “flow-through share” within the meaning of the Income Tax Act (Canada) (the “Tax Act“) and the gross proceeds of the...
HNI Corporation Announces Expiration and Final Results of Exchange Offer
Written by Customer Service on . Posted in Mergers And Acquisitions.
MUSCATINE, Iowa, Dec. 05, 2025 (GLOBE NEWSWIRE) — On August 4, 2025, HNI Corporation (NYSE: HNI; “HNI”) announced a definitive agreement to acquire Steelcase, Inc. (NYSE: SCS; “Steelcase”) in a cash and stock transaction (the “Acquisition”). In connection with the Acquisition, HNI previously announced the commencement of an offer to exchange any and all outstanding 5.125% Notes due 2029 (the “Existing Steelcase Notes”), as issued by Steelcase, for up to $450,000,000 aggregate principal amount of new notes to be issued by HNI (the “New HNI Notes”).
HNI today announced the expiration and final results of the previously announced (A) offer to exchange (the “Exchange Offer”) any and all outstanding Existing Steelcase Notes for New HNI Notes and (B) related solicitation of consents (the “Consent Solicitation”) from the Eligible Holders...
Webus International Limited Issues Clarification on Previous Announcement Related to Expedia Group
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New York, USA, Dec. 05, 2025 (GLOBE NEWSWIRE) — Webus International Limited (“Webus” or the “Company”) provides the following clarification regarding a press release on October 21, 2025, titled “Webus International Limited to Expand Wetour’s Expedia TAAP Partnership with Integration of Expedia Group’s Newly Announced AI Trip Planner and APIs.” (the “Press Release”):
The Press Release contains inaccurate descriptions of the scope of Webus’ relationship with Expedia Group, which Webus now seeks to clarify as follows:Webus’ previous engagement with Expedia Group was limited exclusively to its participation in the Expedia Travel Agent Affiliate Program (TAAP).Webus has never had access to Expedia Group’s Smart Trip AI™, B2B APIs, or any other proprietary AI technologies or trademarks nor were Webus...
Guardian Capital Announces Estimated 2025 Annual Non-Cash Distributions for Guardian Capital ETFs
Written by Customer Service on . Posted in Dividend Reports And Estimates.
TORONTO, Dec. 05, 2025 (GLOBE NEWSWIRE) — Guardian Capital LP (“Guardian Capital”) announces the estimated annual non-cash year-end distributions (the “Non-Cash Distributions”) for the 2025 tax year for the ETF series of the Guardian Capital funds listed below (the “Guardian Capital ETFs”). Please note that these are estimated amounts as of November 14, 2025 and include certain forward-looking information, which may cause the Non-Cash Distributions to change before the Guardian Capital ETFs’ tax year-end on December 15, 2025 or December 31, 2025, as applicable. These estimated amounts are for the Non-Cash Distributions only and do not include the ongoing, regular monthly, quarterly or annual cash distribution amounts which are expected to be announced in a separate press release on or before December 15,...
Sable Announces Adoption of New Equity Incentive Plan
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VANCOUVER, British Columbia, Dec. 05, 2025 (GLOBE NEWSWIRE) — Sable Resources Ltd. (“Sable” or the “Company”) (TSXV: SAE | OTCQB: SBLRF) is pleased to announce that the shareholders of the Company provided near unanimous approval of a new omnibus equity incentive plan (the “Equity Incentive Plan”) at the Company’s annual general and special meeting of shareholders held earlier today (the “Meeting”). All other matters advanced at the Meeting, including setting the board at five members, re-election of directors and appointment of BDO Canada LLP as auditor, were also approved near unanimously.
The Company adopted the Equity Incentive Plan to provide more flexibility than that provided under the previous stock option plan and restricted share unit plan of the Company (collectively, the “Legacy Plans”). The Equity Incentive Plan provides...
