Year: 2025

3 out of 4 patients achieved stable disease (per RECIST v1.1) at the 100 mg APR-1051 dose level in heavily pretreated gastrointestinal and gynecologic malignancies Disease stabilization observed in patients with tumors harboring mutations relevant to WEE1 kinase inhibition (FBXW7, CCNE1, KRAS G12V and TP53) Dose escalation continues, with patients now enrolling in 150 mg cohort Preliminary results from ACESOT-1051 trial through September 17, 2025 to be featured in poster presentation today at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer TherapeuticsDOYLESTOWN, Pa., Oct. 24, 2025 (GLOBE NEWSWIRE) — Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage biopharmaceutical company developing innovative treatments that exploit specific cancer cell vulnerabilities while...

Rebel Engine achieves 72× surge in daily Steam wishlists, signaling accelerating demand and strong pre-launch traction CULVER CITY, Calif., Oct. 24, 2025 (GLOBE NEWSWIRE) —  Snail, Inc. (Nasdaq: SNAL) (“Snail Games” or the “Company”), a leading global independent developer and publisher of interactive digital entertainment, shared highlights from a series of successful game showcases and updates across its growing publishing portfolio, underscoring continued engagement and visibility. Snail Games’ upcoming hybrid action title, Rebel Engine, demonstrated significant momentum during Steam Next Fest, with daily wishlist additions increasing more than 72 times compared to the pre-festival period. This surge contributed to a 46% overall increase in total wishlists, underscoring the game’s accelerating traction ahead of its official...

FUKUOKA, Japan, Oct. 24, 2025 (GLOBE NEWSWIRE) — rYojbaba Co., Ltd. (Nasdaq: RYOJ) (“rYojbaba” or the “Company”), a Japanese labor consulting and health services company, announced a strategic partnership with China Zhongqing International Holdings Co., Ltd. (“Zhongqing International”) to implement the Company’s Free Labor Union Program for Japan’s Technical Intern Training and Specified Skilled Worker Programs. Japan’s Technical Intern Training and Specified Skilled Worker programs were originally designed to bring foreign workers into Japan, allowing them to develop technical skills while addressing the country’s labor needs in essential industries. However, in practice, certain participating companies in the program have been criticized for imposing long working hours, unfair oversight, and human-rights violations. Over the...

Geneva, Switzerland, Oct. 24, 2025 (GLOBE NEWSWIRE) — SEALSQ Corp (NASDAQ: LAES) (“SEALSQ” or “Company”), a company that focuses on developing and selling Semiconductors, PKI, and Post-Quantum technology hardware and software products, today announced that its ordinary shares have been approved for trading on the NASDAQ Global Select Market, effective October 27, 2025. The uplisting from the NASDAQ Capital Market reflects SEALSQ’s continued development, operational progress, and adherence to the highest financial and governance standards required by NASDAQ. The NASDAQ Global Select Market is the highest tier of the NASDAQ Stock Market, reserved for companies that meet the most stringent financial and liquidity standards. SEALSQ’s inclusion in this tier aligns with its vision to expand its presence among...

HOUSTON, Oct. 24, 2025 (GLOBE NEWSWIRE) — FibroBiologics, Inc. (Nasdaq: FBLG) (“FibroBiologics”), a clinical-stage biotechnology company with 270+ patents issued and pending with a focus on the development of therapeutics and potential cures for chronic diseases using fibroblasts and fibroblast-derived materials, today announced that Founder and Chief Executive Officer, Pete O’Heeron, will present at the Bio-Europe 2025 conference taking place November 3-5, 2025, at the Vienna Congress and Convention Center in Vienna, Austria. FibroBiologics will deliver a company presentation at 4:15 p.m. CET on Tuesday, November 4, and will be available for one-on-one investor meetings throughout the event. For more information, please visit FibroBiologics’ website or email FibroBiologics at: info@fibrobiologics.com. About FibroBiologics Based...

LOWELL, Mass., Oct. 24, 2025 (GLOBE NEWSWIRE) — MACOM Technology Solutions Holdings, Inc. (“MACOM”) (Nasdaq: MTSI) plans to announce financial results for its fourth quarter and fiscal year 2025 ended October 3, 2025, before market open on Thursday, November 6, 2025. In conjunction with the release, MACOM will conduct a conference call at 8:30 a.m. Eastern Time on Thursday, November 6, 2025, hosted by Mr. Stephen G. Daly, President and Chief Executive Officer, and Mr. John F. Kober, Senior Vice President and Chief Financial Officer. Please visit MACOM’s Investor Relations Website to register for a user-specific access code for the live call or to access the live webcast. A replay of the call will be available within 24 hours and remain accessible by all interested parties for approximately 90 days. About MACOMMACOM designs and...

NANO Nuclear Energy Inc.NANO Nuclear Energy Holds Milestone Ceremony to Mark Beginning of Drilling Work for First KRONOS MMR™ Micro Modular Reactor Energy System in Partnership with University of Illinois.Tune in today via webcast at 11:30 am Eastern to hear from management, key commercial stakeholders, university officials and distinguished guests as NANO Nuclear celebrates the commencement of real-world work on its micro modular reactor prototype New York, N.Y, Oct. 24, 2025 (GLOBE NEWSWIRE) — NANO Nuclear Energy Inc. (NASDAQ: NNE) (“NANO Nuclear” or “the Company”), a leading advanced nuclear energy and technology company focused on developing clean energy solutions, today is holding a milestone ceremony at the University of Illinois Urbana-Champaign (U. of I.) for the research and commercial prototype of its...

SHENZHEN, China, Oct. 24, 2025 (GLOBE NEWSWIRE) — Fangdd Network Group Ltd. (Nasdaq: DUO) (“FangDD” or the “Company”), a customer-oriented property technology company in China, today announced that it has entered into a convertible note purchase agreement (the “Purchase Agreement”), pursuant to which the Company will issue a convertible promissory note (the “Note”) in a principal amount of US$34,320,000 to an investor through private placement. The Note will be issued to satisfy the Company’s certain payment obligations under an asset purchase agreement dated September 29, 2025 by and between the Company and the investor. Detailed information about the asset purchase agreement can be found in the Company’s current report on Form 6-K furnished to the U.S. Securities and Exchange Commission (the “SEC”) on September 30, 2025. The...

First Characterization of a TDP-43 PET Tracer Published in Nature Communications Showing Potential of AC Immune’s ACI-19626 in Precision MedicineAggregated TDP-43 is a pathological hallmark of neurodegenerative diseases including ALS, FTD and LATE, and a co-pathology in Alzheimer’s and Parkinson’s diseases PET imaging of aggregated TDP-43 could facilitate precision medicine in these diseases, whose shared clinical features complicate differential diagnosis, potentially delaying therapy Based on specificity, sensitivity, and pharmacokinetic properties, ACI-19626 was advanced into a Phase 1 clinical study with initial readout expected in Q4 2025Lausanne, Switzerland, October 24, 2025 — AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision therapeutics for neurodegenerative diseases, today...

Company reports 100%+ customer growth in H1 20251 as CEO joins global leaders at FII9 to discuss AI, capital formation, and the future of global trade LONDON, Oct. 24, 2025 (GLOBE NEWSWIRE) — RedCloud Holdings plc (Nasdaq: RCT) (“RedCloud” or the “Company”) the RedAI trading platform used by Fast Moving Consumer Goods (‘FMCG’) businesses, today announced that CEO Justin Floyd will participate in the Future Investment Initiative (FII9) in Riyadh, Saudi Arabia, from October 27–30, 2025. FII9, one of the world’s largest convenings of policymakers, investors, and innovators, brings together more than 600 speakers and global leaders under the theme “The Key to Prosperity: Unlocking New Frontiers of Growth.” Featured participants span finance and technology—including senior executives from Aramco...