Day: May 4, 2025

PERTH, Australia, May 04, 2025 (GLOBE NEWSWIRE) — Paladin Energy Ltd (ASX:PDN, TSX:PDN, OTCQX:PALAF) (Paladin or the Company) is pleased to announce the appointment of Anne Templeman-Jones as independent non-executive director of the Company. Ms Templeman-Jones is a highly experienced non-executive director who has had a wide-ranging executive career in finance, corporate and private banking roles. She commenced her career in a variety of audit and tax roles with PWC internationally and within Australia. Her banking career included senior positions with ANZ Bank and Westpac. For the past decade Ms Templeman-Jones has held a diverse portfolio of Board roles including with ASX-listed Commonwealth Bank of Australia, global engineering services company Worley Limited which operates across the mining minerals, oil & gas, chemicals...

In the Phase 2 open-label study, REC-4881 (4 mg QD) led to a median 43% reduction (n=6 patients) in polyp burden at the Week 13 assessment at time of data cutoff. Five of six patients (83%) experienced reductions in polyp burden ranging from 31% to 82%, however, one patient showed a substantial increase from baseline. At Week 13, 50% of patients (3 out of 6) achieved ≥1-point improvement in Spigelman stage, a measure of upper GI disease severity. The early safety profile of REC-4881 was generally consistent with that of prior MEK1/2 inhibitors; among 19 patients across Phase 1b and 2, most treatment-related adverse events were Grade 1 or 2, with Grade 3 events in 16% of patients and no Grade ≥4 TRAEs reported to date.SALT LAKE CITY, May 04, 2025 (GLOBE NEWSWIRE) — Recursion (Nasdaq: RXRX), a clinical-stage TechBio company decoding...

New All-Time Handle Record Set for the Kentucky Derby Race, Kentucky Derby Day Program, and Kentucky Derby Week Races LOUISVILLE, Ky., May 03, 2025 (GLOBE NEWSWIRE) — Churchill Downs Incorporated (Nasdaq: CHDN) (the “Company”, “CDI”, “we”) announced today that Sovereignty claimed the Garland of Roses at the 151st running of the Kentucky Derby presented by Woodford Reserve under steady rain and the watchful eyes of over 147,000 eager racing fans. Sovereignty, owned and bred by Godolphin, LLC, trained by William (“Bill”) Mott, and ridden by Junior Alvarado, thundered to the finish to win by a length and a half at 7-1 odds. Sovereignty covered the mile and a quarter in 2:02.31 over a sloppy track. Sired by Into Mischief, Sovereignty now has lifetime earnings of $3.7 million. Wagering from all sources...