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Day: March 19, 2025

Integer Holdings Corporation Enhances Capitalization Structure with the Closing of $1.0 Billion Convertible Senior Notes Offering

~ Strategic transaction to create revolver capacity ~~ Immediately accretive to 2025 adjusted earnings on meaningfully lower interest expense ~ PLANO, Texas, March 18, 2025 (GLOBE NEWSWIRE) — Integer Holdings Corporation (the “Company”) (NYSE: ITGR), a leading medical device contract development and manufacturing organization, announces the closing of its offering of $1.0 billion aggregate principal amount of 1.875% convertible senior notes due 2030 (the “Notes”). In response to strong investor demand at attractive terms, the Company upsized the initial offering of $750 million aggregate principal amount of the Notes to $875 million and the initial purchasers fully exercised their option to purchase an additional $125 million aggregate principal amount of the Notes. “This transaction creates revolver capacity to enable us to continue...

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HUTCHMED and Innovent Jointly Announce that the FRUSICA-2 Phase II/III Study of Fruquintinib and Sintilimab Combination Has Met its Primary Endpoint in Advanced Renal Cell Carcinoma in China

HONG KONG and SHANGHAI and FLORHAM PARK, N.J., March 19, 2025 (GLOBE NEWSWIRE) — HUTCHMED (China) Limited (“HUTCHMED”) (Nasdaq/AIM:​HCM; HKEX:​13) and Innovent Biologics, Inc. (“Innovent”) (HKEX: 01801), today jointly announce that the FRUSICA-2 Phase II/III clinical trial evaluating fruquintinib in combination with sintilimab as second-line treatment for locally advanced or metastatic renal cell carcinoma (“RCC”) in China has met its primary endpoint of progression free survival (“PFS”) per RECIST 1.1 as assessed by blinded independent central review (BICR). The combination of fruquintinib and sintilimab received conditional approval from the China National Medical Products Administration (“NMPA”) for the treatment of patients with advanced endometrial cancer with Mismatch Repair proficient (pMMR) tumors that have failed prior...

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