Day: March 27, 2024

– Deep Cyclic Inhibitor of the MAPK pathway demonstrated strong tumor growth inhibition in preclinical studies of RAF or RAS mutant tumors, both as monotherapy and in combination – – Phase 1 portion of the Phase 1/2a trial designed to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of IMM-6-415 and establish a candidate recommended Phase 2 dose (RP2D) – -Initial PK, PD and safety data expected in 2024 – CAMBRIDGE, Mass., March 27, 2024 (GLOBE NEWSWIRE) — Immuneering Corporation (Nasdaq: IMRX), a clinical-stage oncology company seeking to develop and commercialize universal-RAS/RAF medicines for broad populations of cancer patients, today announced that the first patient has been dosed in its Phase 1/2a trial of IMM-6-415 to treat advanced solid tumors with RAF...

–PRIME status is supported by positive data from the Phase 2b ENLIVEN trial of pegozafermin– –Phase 3 ENLIGHTEN-Fibrosis trial in non-cirrhotic MASH (fibrosis stage F2-F3) patients is enrolling and ENLIGHTEN-Cirrhosis in MASH patients with compensated cirrhosis (F4) is planned to initiate in the second quarter of 2024– SAN FRANCISCO, March 27, 2024 (GLOBE NEWSWIRE) — 89bio, Inc. (Nasdaq: ETNB), a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of liver and cardiometabolic diseases, today announced that the European Medicines Agency (EMA) has granted Priority Medicines (PRIME) status to pegozafermin in patients with MASH. The PRIME status was supported by positive data from the Phase 2b ENLIVEN trial of pegozafermin in patients with non-cirrhotic...

SOUTH SAN FRANCISCO, Calif., March 27, 2024 (GLOBE NEWSWIRE) — Vaxart, Inc. (Nasdaq: VXRT) today announced that Dr. Sean Tucker, Founder and Chief Scientific Officer, will present at the World Vaccine Congress Washington 2024 in Washington, D.C. on Wednesday, April 3, 2024. The Company has appeared repeatedly at the annual event in Washington, D.C. Presentation Information: Title: Moving the needle: Blocking transmission and boosting existing vaccines by oral tablet vaccinationSpeaker: Dr. Sean TuckerDate: Wednesday, April 3, 2024 Time: 3:10 p.m. ETRoom: 207A About VaxartVaxart is a clinical-stage biotechnology company developing a range of oral recombinant vaccines based on its proprietary delivery platform. Vaxart vaccines are designed to be administered using pills that can be stored and shipped without refrigeration and eliminate...

Novel Composition of MDMA Enantiomers leading to next-generation MDMA possibilities TORONTO, March 27, 2024 (GLOBE NEWSWIRE) — PharmAla Biotech Holdings Inc. (“PharmAla” or the “Company”) (CSE: MDMA) (OTC:MDXXF), a biotechnology company focused on the research, development, and manufacturing of LaNeo™ MDMA and novel derivatives of MDMA (MDXX class molecules), is extremely pleased to announce that the US Patent and Trademark Office (USPTO) has indicated it is issuing an allowance for the granting of a patent for ALA-002, the company’s lead investigational MDXX Novel Chemical Entity (NCE). This provides the Company a strong basis for ongoing protection of this intellectual property (IP). ALA-002 is a novel mixture of MDMA enantiomers, consisting of 70-80% R-MDMA and 20-30% S-MDMA. Preclinical testing has shown that the administration...

New Provectus Spinout Company Would Commercialize Combination Therapy of University’s Light Source Medical Device and Provectus’s Pharmaceutical-Grade Rose Bengal SodiumKNOXVILLE, TN, March 27, 2024 (GLOBE NEWSWIRE) — Provectus Biopharmaceuticals, Inc. (“Provectus” or the “Company”) (OTCQB: PVCT) announced today that it has entered into an agreement with the University of Miami (the “University”) for the exclusive worldwide license of the University’s intellectual property related to photodynamic antimicrobial therapy (“PDAT”) for treating bacterial, fungal, and parasitic (acanthamoeba) infections of the eye. This agreement contemplates Provectus forming a majority-owned start-up company in which the University would be a minority equity shareholder, aimed at developing and commercializing the University’s PDAT medical device...

TULSA, Okla., March 27, 2024 (GLOBE NEWSWIRE) — Ladybug Resource Group, Inc.; (OTC PINK: LBRG) (“Ladybug” or the “Company”), remarks on the significant milestone achieved by the acquisition of its first three websites which marks a pivotal moment for Ladybug, enhancing revenue potentials and establishing a strong groundwork for a series of planned acquisitions over the coming years. This key move demonstrates the Company’s insightful planning and skill in strengthening its market position. The three websites can be visited by clicking on the hyperlinks to the following web addresses. –        https://growhousenutraceuticals.com–        https://www.nutra55.com–        https://www.purelypregna.com The acquisition of these websites underscores Ladybug’s strategic foresight and...

VANCOUVER, British Columbia, March 27, 2024 (GLOBE NEWSWIRE) — Treatment.com AI Inc. (CSE: TRUE, OTC: TREIF, Frankfurt: 939) (the “Company” or “Treatment”) is pleased to announce that the Company has received funding from The National Institute of Health (“NIH”) to develop a culturally sensitive AI approach for collecting family medical history. Treatment has partnered with Rush River Research in Minneapolis to develop an Artificial Intelligence (AI) approach for collecting information about family medical history that is culturally sensitive and appropriate for African-American families. Current methods used by clinicians to collect family medical histories often do not satisfactorily capture important information from blended families or non-traditional relationships commonly found in racial or ethnic minority communities. The...

Article highlights Company’s AI-Driven Solutions to Call Center Challenges CHICAGO, March 27, 2024 (GLOBE NEWSWIRE) — Vocodia Holdings Corp. (CBOE: VHAI) (“Vocodia” or the “Company”), an AI software company that builds practical AI functions, has been recognized in a USA Today article for its innovative solutions that aim to enhance the customer service experience by eliminating call center hold times. The piece, titled “Vocodia’s Conversational AI Eliminates Call Center Hold Times,” highlights the company’s approach to addressing the universal frustration of waiting on hold, a situation that consumes an average of 40 days over a person’s lifetime. The article features Vocodia’s Digital Intelligent Sales Agents or DISAs, an AI-powered program that handles comprehensive sales and customer support channels...

SaverOne’s solution to be provided to IVECO’s customers under a SaaS model Petah Tikvah, Israel, March 27, 2024 (GLOBE NEWSWIRE) — SaverOne 2014 Ltd. (Nasdaq: SVRE, TASE: SVRE), a technology company that develops and sells transportation safety solutions, today announced that it has signed an OEM agreement with IVECO, the brand of Iveco Group N.V. (EXM: IVG) that designs, manufactures and markets light, medium and heavy commercial vehicles. The agreement seals the collaboration to develop a solution to prevent driver distraction from cellphone use. The OEM agreement covers the integration of SaverOne’s safety technology within IVECO’s vehicles through their manufacturing line. Initially, throughout 2024, SaverOne’s software will be integrated within IVECO’s hardware. Future further evolutions, may include the integration of SaverOne’s...

Presentation on Tuesday, April 9, 2024, at 8:30 am ET MILTON, N.Y., March 27, 2024 (GLOBE NEWSWIRE) — Sono-Tek Corporation (Nasdaq: SOTK), the leading developer and manufacturer of ultrasonic coating systems, today announced that it will be presenting at the 14th Annual LD Micro Invitational at the Sofitel New York on April 8th-9th, 2024. The event is expected to feature 80 companies presenting in half-hour increments, as well as private 1:1 meetings.  Sono-Tek is scheduled to present on Tuesday, April 9, 2024, at 8:30 am ET. Dr. Christopher Coccio, Executive Chairman, and Steve Harshbarger, Chief Executive Officer and President, will be leading the presentation. Interested parties are invited to register to watch the presentation virtually here: https://ldinv14.sequireevents.com/ About Sono-Tek Sono-Tek Corporation is the leading...