Day: September 21, 2023

– New data from multi-dose GLP toxicology study of SNS-101 in cynomolgus monkeys further support exceptional PK and safety profile – – Mechanistic mouse data show SNS-101 drives tumor macrophages to adopt an immunostimulatory, anti-tumor phenotype – BOSTON, Sept. 21, 2023 (GLOBE NEWSWIRE) — Sensei Biotherapeutics, Inc. (Nasdaq: SNSE), a clinical stage immuno-oncology company focused on the discovery and development of next-generation therapeutics for cancer patients, today will present new preclinical data from SNS-101, a clinical-stage conditionally active, human monoclonal antibody targeting the immune checkpoint VISTA (V-domain Ig suppressor of T cell activation), at the Seventh Annual CRI-ENCI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held on September 20...

Figure 1Thorn Project and Copper Target Location Map with Copper Geochemistry.Figure 2Camp Creek Drill Hole Intersections at -400m Elevation Below Sea Level.Figure 3Hole THN23-261 Photograph of Mineralized Core at 955.50m Depth.Figure 4Cross Section of the Camp Creek Drill Target.Figure 5Hole THN23-261 Core Photograph at 1231.49m Depth.Figure 6Hole THN23-261 Core Photograph at 1461.50m Depth.VANCOUVER, British Columbia, Sept. 21, 2023 (GLOBE NEWSWIRE) — Brixton Metals Corporation (TSX-V: BBB, OTCQB: BBBXF) (the “Company” or “Brixton”) is pleased to announce the first 2023 drill results from its Camp Creek Copper Porphyry Target on its wholly owned Thorn Project located in Northwest British Columbia, Canada. HighlightsHole THN23-261 is the longest copper interval drilled at...

FILSPARI® (sparsentan) achieved a clinically meaningful difference vs. irbesartan in eGFR total slope (1.0 mL/min/1.73m2 per year) [p= 0.058] and eGFR chronic slope (1.1 mL/min/1.73m2 per year) [p=0.037]. Patients treated with FILSPARI over two years exhibited one of the slowest annual rates of kidney function decline seen in a clinical trial of IgAN patients (-2.7 to -2.9 mL/min/1.73m2 per year) eGFR chronic slope was statistically significant with respect to the confirmatory endpoint for the EU All topline efficacy endpoints favored FILSPARI FILSPARI was well-tolerated with a consistent safety profile comparable to irbesartan across all clinical trials conducted to date, supporting long-term use The Company will meet with regulators and expects to submit a supplemental New Drug Application (sNDA) in 1H 2024 for full approval in the...

Figure 1Tenement map of CIO interests in the Dalot Mineral FieldFigure 2Mineral Resource within the optimised pit shellVANCOUVER, British Columbia, Sept. 21, 2023 (GLOBE NEWSWIRE) — Central Iron Ore Ltd. (CIO – TSX.V) (“CIO” or “the Company”) is pleased to announce the settlement of proceedings it commenced in the Supreme Court of Western Australia against SilverStream SEZC. The Company has held 100% beneficial ownership in its British King Mine Project since October 2020. As a result of the settlement, the Company will now be in a position to have its entire 100% ownership of the British King Gold Project registered on the title of the relevant tenements. David Deitz the CEO comments: “We are very pleased that with the resolution of tenure and registration of 100% title. CIO can continue to focus on the advancement...

VANCOUVER, British Columbia, Sept. 21, 2023 (GLOBE NEWSWIRE) — Interfield Global Software Inc. (NEO: IFSS) (the “Company”) is pleased to announce that its 100% owned site E-Commerce site Equipment Hound, the leading B2B e-commerce marketplace for industrial equipment, has announced that JRL Energy Inc. (“JRL Energy”), a renowned USA based mining company, has taken a significant step by joining as a premium member on the Equipment Hound platform. As a premium member, JRL Energy gains exclusive access to a range of benefits designed to enhance their ability to procure cost effective mining equipment and to monetize idle assets on the Equipment Hound platform. These benefits include priority placement in search results, advanced product showcase features, and detailed analytics tools to measure and optimize their online performance. The...

Successful Audit of the Company’s State-of-the-Art Manufacturing Facility Represents a Key Milestone Toward Plan to Commercialize D-PLEX₁₀₀ Globally PETACH TIKVA, Israel, Sept. 21, 2023 (GLOBE NEWSWIRE) — PolyPid Ltd. (Nasdaq: PYPD) (“PolyPid” or the “Company”), a late-stage biopharma company aiming to improve surgical outcomes, today announced that the Israeli Ministry of Health has completed a successful Good Manufacturing Practice (GMP) audit of the Company’s manufacturing facility without any critical or major findings. The audit was conducted as part of the Ministry of Health’s routine evaluation of PolyPid’s manufacturing process for D-PLEX100. The audit concluded that PolyPid’s manufacturing facility, process and quality system conform to the requirements of current GMP for medicinal products. This audit is also...

NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR FOR DISSEMINATION IN THE UNITED STATES QUEBEC CITY, Sept. 21, 2023 (GLOBE NEWSWIRE) — Robex Resources Inc. (TSXV: RBX) (“Robex” or the “Company”) announces management changes, effective as of September 21st, 2023. Since the beginning of their first investment in Robex in 2013, the Cohen family members supported the Company by developing and operating the Nampala mine in Mali. They have been constantly engaged in operating within the industry standard thanks to their key executive positions, and long-term financial backing. They have been committed to deliver external growth strategy with the business combination with Sycamore Mining Limited in 2022. The past two years have been transformational for the Company with (i) the integration of Sycamore and teams, and (ii) the...