Month: June 2023

Lilium signs agreement with Heli-Eastern for the purchase of Lilium Jets and the development of premium eVTOL services in China Lilium signs agreement with Heli-Eastern for the purchase of Lilium Jets and the development of premium eVTOL services in China• The two companies will jointly develop eVTOL services across the Guangdong–Hong Kong–Macao Greater Bay Area • Heli-Eastern intends to purchase 100 Lilium Jets • Heli-Eastern will operate the Lilium Jet fleet in the region and provide maintenance and crewing servicesPARIS, June 18, 2023 (GLOBE NEWSWIRE) — Lilium N.V. (NASDAQ: LILM), developer of the first all-electric vertical take-off and landing (eVTOL) jet, announced an agreement with Shenzhen Eastern General Aviation Co., Ltd (Heli-Eastern), a major low-altitude general aviation carrier and helicopter service...

– Oral presentation of results showed sustained improvements through Week 52, as well as safety and tolerability similar to that previously reported for the initial 26-week blinded portion of the Phase 3 PaTHway Trial – At Week 52, 95% of patients treated with TransCon PTH achieved independence from conventional therapy – TransCon PTH treatment improved mean patient-reported disease symptom and health-related quality of life scores, starting at the first scheduled follow up after randomization or after switching from placebo and sustained through Week 52 COPENHAGEN, Denmark, June 17, 2023 (GLOBE NEWSWIRE) — Ascendis Pharma A/S (Nasdaq: ASND) today reported one-year (Week 52) data from its ongoing Phase 3 PaTHway Trial of TransCon PTH in adults with hypoparathyroidism. The data showed that treatment with TransCon...

— Mean BMI reduction of 21.0% from baseline observed in 13 patients at six months, showing progression from 16.8% mean BMI reduction at 16 weeks — — Phase 3 trial evaluating setmelanotide in acquired hypothalamic obesity ongoing; completion of enrollment expected 1Q 2024 — BOSTON, June 17, 2023 (GLOBE NEWSWIRE) — Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a commercial-stage biopharmaceutical company focused on transforming the lives of patients and their families living with hyperphagia and severe obesity caused by rare melanocortin-4 receptor (MC4R) pathway diseases, today announced data that showed meaningful weight loss was sustained and progressed in patients with hypothalamic obesity treated with setmelanotide for six months as part of the long-term extension of its Phase 2 trial.    “Hypothalamic...

Figure 1 UPCR % Change With Atacicept 150 mg at Week 36Figure 2 eGFR % Change With Atacicept 150 mg Through Week 36New data at week 36 shows atacicept 150 mg resulted in a delta of 43% versus placebo in mean proteinuria reduction in per-protocol analysis and demonstrated statistically significant stabilization of eGFR versus placebo in this high-risk population Atacicept was well tolerated with safety profile similar to placebo Positive results support atacicept 150 mg as a potential disease-modifying treatment for patients with IgA nephropathy; Phase 3 (ORIGIN 3) clinical trial initiated in June 2023 Conference call and webcast to take place on June 20th, 2023, at 8:00 a.m. ET to further discuss results BRISBANE, Calif., June 17, 2023 (GLOBE NEWSWIRE) — Vera Therapeutics, Inc. (Nasdaq: VERA), a late-stage biotechnology company...

BEIJING, China, June 17, 2023 (GLOBE NEWSWIRE) — Li Auto Inc. (“Li Auto” or the “Company”) (Nasdaq: LI; HKEX: 2015), a leader in China’s new energy vehicle market, today hosted a family tech day presenting the Company’s progress and plans in electrification and intelligentization. On the HPC BEV side, the Company has optimized its battery cells and upgraded its thermal management system to fully leverage the battery’s maximum 5C charging rate, enabling a peak charging power of over 500 kW. The Company has also started to self-build its 5C super charging network. As for intelligentization, the Company presented its progress and plans for smart space and autonomous driving, with city NOA beta testing planned for early bird users in Beijing and Shanghai in June. In addition, the Company plans to release commute NOA to early bird users...

CHK-336 was generally well tolerated in healthy volunteers (HV) who received single doses up to 500 mg and multiple doses up to 60 mg for 14 days Pharmacokinetics (PK) was well characterized with dose-proportional exposures and a half-life that supports once-daily dosing Successful implementation of a novel 13C2-glycolate tracer established proof-of-mechanism of CHK-336 to block hepatic oxalate production in HVs One serious adverse event (SAE) of anaphylaxis occurred in a multiple ascending dose HV who received one 125 mg dose CHK-336, resulting in voluntary study pause Additional research presented on the impact of maladaptive tubular epithelial cells on progression of chronic kidney diseaseSEATTLE, June 17, 2023 (GLOBE NEWSWIRE) — Chinook Therapeutics, Inc. (Nasdaq: KDNY), a biopharmaceutical company focused on the discovery,...

Restructuring agreement with K2 HealthVentures (K2HV) to fully discharge and satisfy outstanding debt owed to K2HV for the prepayment of $27.5 million and the granting of contingent value rights and warrantsAdditional reduction-in-force by approximately 44% as it continues to explore strategic alternativesAUSTIN, Texas, June 16, 2023 (GLOBE NEWSWIRE) — Molecular Templates, Inc. (Nasdaq: MTEM, “Molecular Templates,” or “MTEM”), a clinical-stage biopharmaceutical company focused on the discovery and development of proprietary targeted biologic therapeutics, engineered toxin bodies (“ETBs”), to create novel therapies with potent differentiated mechanisms of action for cancer, announced today that it has entered into a restructuring agreement (“Amending Agreement”) with K2 HealthVentures (“K2HV”) to satisfy and discharge MTEM’s...

VANCOUVER, British Columbia, June 16, 2023 (GLOBE NEWSWIRE) — Imperial Metals Corporation (the “Company” or “Imperial”) (TSX:III) is pleased to announce that it is planning to issue unsecured non-convertible debentures (the “Debentures”), with an aggregate principal amount of up to $35,000,000 on a non-brokered private placement basis (the “Private Placement”). The Debentures have a maturity date of July 1, 2024 and bear interest at a rate of 12.0% per annum, with interest paid semi-annually in cash, with the first payment due January 1, 2024. The proceeds from the Private Placement are intended to be used to fund the operation and development at the Red Chris mine and for general working capital purposes. N. Murray Edwards has agreed to purchase up to $21,000,000 of the Debentures. In addition, directors and officers of the Company...

VANCOUVER, British Columbia, June 16, 2023 (GLOBE NEWSWIRE) — Liquid Media Group Ltd. (the “Company”) (Nasdaq: YVR) announces today the sale of its wholly-owned subsidiary IndieFlix Group for an aggregate purchase price of US$1.2M. The purchase price was paid in the form of a ten-year promissory note bearing interest at 6.0%. Payments under the promissory note commences 18 months from issuance with 10% of the IndieFlix Group’s gross monthly revenues payable as received to be applied to such payments, with all unpaid and outstanding principal amount, if any, due on the maturity date. The promissory note is secured by all of the shares of IndieFlix Group. Liquid Media Interim CEO, Joshua Jackson, commented “We believe this transaction best aligns with the direction of the company as we look to streamline and position our assets for...