Day: June 27, 2023

89% of all aflibercept 8 mg patients maintained ≥12-week dosing intervals through two years Of those assigned to a 16-week dosing regimen at baseline, 83% maintained ≥16-week dosing intervals through two years Many patients met the extension criteria for even longer dosing intervals, including 43% for ≥20-week intervals and 27% for 24-week intervals Visual gains and safety of aflibercept 8 mg remained consistent with the established profile of EYLEA® (aflibercept) 2 mg Injection TARRYTOWN, NY, June 27, 2023 (GLOBE NEWSWIRE) — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced top-line, two-year (96 weeks) data for aflibercept 8 mg from the pivotal PHOTON trial in patients with diabetic macular edema (DME). During the trial, aflibercept 8 mg patients were initially randomized to either 12- or 16-week dosing intervals...

No issues with clinical efficacy or safety, trial design, labeling or drug substance manufacturing were identified in the CRL No additional clinical data or trials have been requested TARRYTOWN, N.Y., June 27, 2023 (GLOBE NEWSWIRE) — Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) for the Biologics License Application (BLA) for aflibercept 8 mg for the treatment of patients with wet age-related macular degeneration (wAMD), diabetic macular edema (DME) and diabetic retinopathy (DR), solely due to an ongoing review of inspection findings at a third-party filler. The CRL did not identify any issues with the aflibercept 8 mg clinical efficacy or safety, trial design, labeling or drug substance manufacturing, and no additional...

Nokia CorporationStock Exchange Release27 June 2023 at 21:00 EEST Nokia Corporation: Repurchase of own shares on 27.06.2023 Espoo, Finland – On 27 June 2023 Nokia Corporation (LEI: 549300A0JPRWG1KI7U06) has acquired its own shares (ISIN FI0009000681) as follows:Trading venue (MIC Code) Number of shares Weighted average price / share, EUR*XHEL 336,427 3.74CEUX 22,188 3.75AQEU 10,418 3.74TQEX 6,967 3.74Total 376,000 3.74* Rounded to two decimals On 3 February 2022, Nokia announced that its Board of Directors is initiating a share buyback program under the authorization granted by Nokia’s Annual General Meeting on 8 April 2021 to return up to EUR 600 million of cash to shareholders in tranches over a period of two years. The second phase of the share buyback program in compliance with the Market Abuse Regulation (EU)...

Article L.233-8 II du Code de commerce et article 223-16 du Règlement général de l’Autorité des marchés financiers Dénomination sociale de l’émetteur :         Derichebourg119, Avenue du Général Michel Bizot75012 PARIS  Date   Nombre total d’actions composant le capital social   Nombre total de droits de vote  31/05/2023   159 397 489   Nombre de droits de vote théoriques : 227 410 702                      Nombre de droits de vote exerçables* : 227 410 702                  * Nombre de droits de votes exerçables = nombre de droits de vote théoriques (ou nombre total de droits de vote attachés aux actions) – actions privées du droit de vote. Code ISIN : FR 0000053381 – DBGAttachmentDroits de vote au 31 mai 2023

Rapid7’s support of AWS AppFabric continues its commitment to extending monitoring, detection, and response for the cloud BOSTON, June 27, 2023 (GLOBE NEWSWIRE) — Rapid7, Inc. (NASDAQ: RPD), a leader in cloud risk and threat detection, today announced that InsightIDR integrates with AWS AppFabric, announced today by Amazon Web Services (AWS). Rapid7’s ability to support AWS AppFabric at launch expands their relationship with AWS and affirms the company’s commitment to extending customers’ monitoring, detection, and response capabilities for the cloud. As organizations continue to use an increasing number of software as a service (SaaS) applications in their network infrastructure, security professionals must secure these apps with limited visibility into their usage data. This lack of visibility, primarily due to disparate methods...

Terraces at The Station by Toll Brothers A new luxury townhome community by Toll Brothers, Terraces at The Station, is now open in Sunnyvale, California.Terraces at The Station by Toll Brothers “Terraces at The Station is a community that truly reflects the evolving needs of today’s home buyers in Sunnyvale, offering exceptional design in an outstanding location,” said Todd Callahan, Regional President of Toll Brothers for the Pacific Region.SUNNYVALE, Calif., June 27, 2023 (GLOBE NEWSWIRE) — Toll Brothers, Inc. (NYSE:TOL), the nation’s leading builder of luxury homes, today announced the highly anticipated opening of Terraces at The Station, a luxury community offering 140 townhomes and resort-style onsite amenities in Santa Clara County, California. Home buyers are invited to visit the Sales Center and tour the professionally...