Day: June 7, 2023

4D-710 Clinical Activity & Biomarker Summary for Cohort 1 (n=3) Phase 1 Dose Exploration Cohort 1 Interim Clinical Activity Data: Table 1Reported data from cohort 1 (n=3, 1E15 vg dose) of cystic fibrosis modulator treatment ineligible/intolerant participants with 9-12 months follow-upQuality of life outcomes measured by Cystic Fibrosis Questionnaire-Revised respiratory symptom score (CFQ-R-R) meaningfully improved for all three participantsPercent predicted forced expiratory volume in one second (ppFEV1) meaningfully improved in participant with moderate ppFEV1 impairment at baseline; ppFEV1 maintained stable in participants with normal or mild impairment at baselineBronchoscopy sample results demonstrated widespread and consistent expression of the cystic fibrosis transmembrane conductance regulator (CFTR) transgene...

Lille (France); Cambridge (Massachusetts, United States); Zurich (Switzerland); June 7, 2023 – GENFIT (Nasdaq and Euronext: GNFT), a late-stage biopharmaceutical company dedicated to improving the lives of patients with rare and severe liver diseases, today announced that it will present new data at the EASL Congress which will take place on June 21-24, 2023 in Vienna, Austria. Posters and Presentations GENFIT has had three abstracts accepted for poster sessions. Presentations include preclinical data showing the beneficial effects of nitazoxanide (NTZ) in an Acute-on-Chronic Liver Failure (ACLF) disease model, NIS2+™ as an effective screening tool for optimizing patient selection in clinical trials targeting at-risk Non-Alcoholic Steatohepatitis (NASH) and NIS2+™ as the most adapted Non-Invasive Test (NIT) for an efficient...

MARLBOROUGH, Mass., June 07, 2023 (GLOBE NEWSWIRE) — Akoya Biosciences, Inc. (Nasdaq: AKYA) (“Akoya”), The Spatial Biology Company®, today announced it has launched an underwritten public offering of shares of its common stock (the “Offering”). In addition, Akoya expects to grant the underwriters a 30-day option to purchase additional shares of its common stock. The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering. Akoya intends to use the net proceeds from the Offering for working capital and general corporate purposes. Morgan Stanley and Piper Sandler, are acting as joint book-running managers for the Offering. The securities described above are being offered by Akoya pursuant to a shelf...

VANCOUVER, British Columbia, June 07, 2023 (GLOBE NEWSWIRE) — American Pacific Mining Corp (CSE: USGD / FWB: 1QC / OTCQX: USGDF) (“APM” or the “Company”) is pleased to announce that Michael Gentile has exercised a total of 8,181,964 common share purchase warrants (each a “Warrant”) at $0.16 per common share (each a “Share”) for total proceeds of $1,309,114.24 received by the Company. Following the Warrant exercise, Mr. Gentile holds 22,552,932 Shares and 2,236,974 Warrants, representing 11.48% of the issued and outstanding Shares of the Company on a non-diluted basis, and, on a partially diluted basis, (i.e., assuming full exercise of the Warrants), Mr. Gentile would hold a total of 24,789,906 Shares, representing approximately 12.48% of the Company’s issued and outstanding Shares. The Company also announces that it intends to...

BBS-Bioactive Bone Substitutes Plc, Company Announcement, 7 June 2023 at 10.30 p.m. EEST BBS-Bioactive Bone Substitutes Plc: 57% of warrants 2-2022 (TO2) used for the subscription of shares, company raises EUR 162,000 in gross proceeds. The subscription period for BBS-Bioactive Bone Substitutes Plc’s (“BBS” or “Company”) first series of warrants 2-2022 (TO2) ended on 2 June 2023. In total, 254 580 warrants 2-2022 (TO2) were used, corresponding to approximately 57.2 percent of the total number of warrants. BBS received approximately EUR 162,000 in gross proceeds before expenses. The company’s Board of Directors has today approved the share subscriptions. The subscription price was EUR 0.65 and SEK 7.38 per share. The subscription period for the shares was 22 May – 2 June 2023. The shares are expected to be registered in the...

Five poster presentations showing :the correlation between the improvement of hepatic steatosis and a robust increase in adiponectin levels, improvement in lipid profile and glycemic control in patients with non-cirrhotic NASH treated with lanifibranor. the Early improvement in ALT or AST being predictive of response pattern of liver histology as well as non-invasive hepatic and cardiometabolic biomarkers observed after 24-week treatment with lanifibranor in patients with non-cirrhotic NASH. the improvement of portal hypertension and splanchnic circulation independently of fibrosis reduction and metabolic improvement following lanifibranor treatment in a mouse model of prehepatic portal hypertension. the reduction of the increased portal pressure and improvement of steatosis in a rat model of early NAFLD following a 4-week lanifibranor...

Thumzup Media Corporation Sock PandaAvailable in the App Store and Google Play, Thumzup Enables Virtually Everyone to Earn Cash Rewards for Posting on Social Media about the Brands They Love Los Angeles, CA, June 07, 2023 (GLOBE NEWSWIRE) — Thumzup Media Corporation (“Thumzup” or the “Company”) (OTCQB: TZUP) is excited to welcome e-commerce brand Sock Panda to its cash rewards digital social media branding platform. The Thumzup mobile app, which is available for download in the App Store and Google Play, incentivizes virtually everyone to become social media advocates for the brands they enjoy by paying them cash for approved posts. “From fuzzy socks and slouch socks to toe #socks and knee highs, Sock Panda has a sock for every foot, and we’re excited to welcome them to the Thumzup platform,” stated Robert...

ATLANTA, June 07, 2023 (GLOBE NEWSWIRE) — Gray Television, Inc. (“Gray”) (NYSE: GTN) received the 2023 Celebration of Service to America Award for TV Ownership Group at a formal ceremony in Washington, DC, yesterday. The award recognized the outstanding work of Gray’s InvestigateTV unit and its series, “The Sixth,” which exposed a critical shortage of public defenders across the country. Each year, the National Association of Broadcasters Leadership Foundation presents the Celebration of Service to America Awards to honor excellence in community service by local radio and television stations. In addition, the Foundation selected Gray’s KTTC in Rochester, Minnesota, as its Small Market Television Winner for the station’s nearly 70-year long “Fifth District Eagles Cancer Telethon,” which has raised over $22 million since its inception...

HeritageOneSM will increase access to affordable mortgages for tribal members living in tribal areas MCLEAN, Va., June 07, 2023 (GLOBE NEWSWIRE) — Freddie Mac (OTCQB: FMCC) today announced the launch of a new mortgage product to support members of Native American communities. HeritageOne will provide affordable financing options for single-family properties on tribal lands in rural areas, creating greater access to homeownership. It will also provide financial counseling and other resources to members of Native American tribes, especially first-time homebuyers. “With HeritageOne, we are again breaking new ground in our efforts to safely and responsibly expand opportunities in traditionally underserved communities,” said Sonu Mittal, Single-Family Senior Vice President of Acquisitions at Freddie Mac. “Our commitment to make home...