Day: November 29, 2022

<div>Allogene Therapeutics R&D Showcase Features Hematologic and Solid Tumor Advances Across its AlloCAR T™ Platform</div>

Allogene Therapeutics R&D Showcase Features Hematologic and Solid Tumor Advances Across its AlloCAR T™ Platform

Hematology Franchise: Lead CD19 and BCMA Programs Demonstrated Deep, Durable Responses CD19 Program: Phase 1 Studies Support Ongoing ALLO-501A Potentially Pivotal Phase 2 Trial in Relapsed/Refractory (R/R) Large B Cell Lymphoma (LBCL) One-Time Cell Dosing with Proprietary Lymphodepletion (Single Dose FCA90) Resulted in 67% Overall Response Rate (ORR) and 58% Complete Response (CR) Rate Responses in Patients that Received Single Dose FCA90 Were Durable with a 50% CR Rate at Both Six and 12 Months with Longest CR Ongoing at 26+ Months No Observed Dose Limiting Toxicities (DLTs), Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) or Graft-vs-Host Disease (GvHD) 92% of Enrolled Patients Received Investigational Product, 100% Manufactured and Released Per Product Specifications, and Treatment Initiation Within Two Days of Enrollment BCMA...

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EF Hutton Expands Healthcare Franchise with Appointments of Veteran Equity Research Analysts 

EF Hutton Expands Healthcare Franchise with Appointments of Veteran Equity Research Analysts 

New York, NY, Nov. 29, 2022 (GLOBE NEWSWIRE) — via NewMediaWire — EF Hutton, division of Benchmark Investments LLC (“EF Hutton”), today announced a series of strategic hires enhancing the company’s Healthcare Equity Research Department. Tony Butler, Senior Managing Director, Elemer Piros, Managing Director, Fozia Ahmed, Associate and Tashdid Hasan, Associate, will join the team of Healthcare Equity Research Analysts at EF Hutton. Joseph T. Rallo, CEO of EF Hutton, stated, “Four major healthcare appointments demonstrates that EF Hutton is committed to bringing on top tier talent. We are excited to have built one of the most experienced healthcare research groups on Wall Street. In a time of market uncertainty, we believe Dr. Butler and Dr. Piros will continue to deliver valuable insights and differentiated research to EF Hutton’s...

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First Citizens Bank’s 2022 Holiday Campaign Celebrates Teen Cancer America’s 10th Anniversary

First Citizens Bank’s 2022 Holiday Campaign Celebrates Teen Cancer America’s 10th Anniversary

First Citizens Bank 2022 Holiday Campaign Celebrates Teen Cancer America’s 10th Anniversary To honor Teen Cancer America’s 10th anniversary of helping teens and young adults with cancer, First Citizens Bank is encouraging everyone to make a donation to the nonprofit this holiday season. Visit firstcitizens.com/teen-cancer-america. RALEIGH, N.C., Nov. 29, 2022 (GLOBE NEWSWIRE) — To honor Teen Cancer America’s (TCA) 10th anniversary of helping teens and young adults with cancer, First Citizens Bank is encouraging everyone to make a donation to the nonprofit this holiday season. The bank’s holiday campaign for TCA runs through Dec. 31, 2022. “It’s 10 years of hope, and just one minute to help,” said Jeff Ward, First Citizens’ chief strategy officer and TCA national board member. “Teen Cancer America has made tremendous strides...

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Sorrento Releases Positive Topline Results from the Phase I Study Completed in Australia and Preliminary Results from a Phase Ib Study in China with STI-1558, an Oral M(pro) Inhibitor as a Standalone Treatment for COVID-19 without the Need for Ritonavir Boosting

Sorrento Releases Positive Topline Results from the Phase I Study Completed in Australia and Preliminary Results from a Phase Ib Study in China with STI-1558, an Oral M(pro) Inhibitor as a Standalone Treatment for COVID-19 without the Need for Ritonavir Boosting

Topline safety and pharmacokinetic (PK) data from the Phase I single ascending dose (SAD)/multiple ascending dose (MAD) study of STI-1558 in 58 healthy volunteers in Australia are now available. The SAD portion of the study evaluated doses from 300 mg to 2,000 mg and the MAD portion evaluated 300 mg, 600 mg or 800 mg BID (twice a day daily) for 7.5 days. Overall, STI-1558 was well-tolerated at these doses with most subjects reporting no adverse events (AEs). There was no dose limiting toxicity during the study. There were no severe or serious AEs, no premature discontinuation of STI-1558 due to an AE, and no deaths. Most AEs were mild and unrelated. The PK profile was dose proportional; the mean AUC (h*µg/mL) in the SAD 300 mg, 600 mg, 1200 mg and 2000 mg cohorts was 14.3, 29.2, 43.8 and 93.3, respectively. In the MAD cohorts (300 mg...

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Sumo Logic Accelerates Data Insights to Modernize Security Operations

Sumo Logic Accelerates Data Insights to Modernize Security Operations

Sumo Logic supports the launch of Amazon Security Lake with cloud-native innovations that remove complexity and lower costs LAS VEGAS, Nov. 29, 2022 (GLOBE NEWSWIRE) — AWS re: Invent 2022 — Sumo Logic (NASDAQ: SUMO), the SaaS analytics platform to enable reliable and secure cloud-native applications, today announced support for the launch of Amazon Security Lake from Amazon Web Services (AWS). Sumo Logic will showcase its observability and security solutions for AWS from Booth #1120 at AWS re:Invent 2022 this week in Las Vegas. Amazon Security Lake automatically centralizes an organization’s security data from cloud, on-premises, and custom sources into a purpose-built data lake stored in a customer’s account. Sumo Logic ingests data from Amazon Security Lake and provides broad visibility across all AWS, on-premise, and...

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Ranchero Gold Announces Completion of Debt Facility

Ranchero Gold Announces Completion of Debt Facility

VANCOUVER, British Columbia, Nov. 29, 2022 (GLOBE NEWSWIRE) — Ranchero Gold Corp. (“Ranchero” or the “Company”) (TSX.V: RNCH) is pleased to announce the closing of its draw-down facility (“Loan”) with American PT Metals LLC (“American Metals”) (refer to the Press Release on September 26, 2022). The Loan is made to an indirect wholly-owned subsidiary of the Company, Minera y Metalurgia Paika, S.A. de C.V. (the “Borrower”) from Mexico Minerales y Metales Earth, S.A. de C.V. (the “Lender”), a subsidiary of American Metals, in the aggregate principal amount of US$500,000 pursuant to the terms of the loan agreement dated November 16, 2022. The outstanding principal amount of the Loan will accrue interest at a rate of 12% per annum, to be repaid by the maturity date of October 31, 2024. If the Borrower does not pay the full amount to...

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Become a “Knight of AI” by Joining Rackspace Technology at AWS re:Invent

Become a “Knight of AI” by Joining Rackspace Technology at AWS re:Invent

Visit the Onica by Rackspace Technology re:Invent booth 244 for “Knights of AI” hands-on, interactive computer vision demonstration SAN ANTONIO, Nov. 29, 2022 (GLOBE NEWSWIRE) — Rackspace Technology® (NASDAQ: RXT)— a leading end-to-end, multicloud technology solutions company, today announced the “Knights of AI” in the Onica by Rackspace Technology booth 244 at re:Invent. “Knights of AI” is a hands-on, interactive computer vision demonstration that was created by the Rackspace Technology data science and cloud-native teams and showcases how serverless and AI/ML technologies combine to create an A(I)dventurous experience. Rackspace Technology is celebrating 11 years of sponsoring re:Invent as an AWS Premier Consulting Partner and Platinum Sponsor of AWS re:Invent 2022. In addition to “Knights of AI”, Onica by Rackspace Technology...

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Quad M Solutions Inc. Signs Letter of Intent to assign 800 employees staffing contracts for $5-7 million

Quad M Solutions Inc. Signs Letter of Intent to assign 800 employees staffing contracts for $5-7 million

Company believes deal assignment will close by year end Garland, TX, Nov. 29, 2022 (GLOBE NEWSWIRE) — Quad M Solutions Inc. (OTCPK:MMMM) has executed a letter of intent to assign 800 employees contracts to a well funded Reinsurance company for the cash value of approximately $5-7 million. Mr Joseph Frontiere, CEO, said “ Recently we were approached by several entities inquiring to purchase staffing contracts for approximately $8,000/contract. We have gone through a thorough due diligence review by a well funded, US Reinsurance company and signed a letter of intent. I expect the deal to close by year end. These contracts are among our earliest employee contracts and have not seen price increases in several years. If we value our remaining contracts at the same price for which we are assigning those contracts, our remaining book...

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Cumulus Media and Signal Hill Insights Release Podcast Download – Fall 2022 Report Revealing Latest Podcast Trends

Cumulus Media and Signal Hill Insights Release Podcast Download – Fall 2022 Report Revealing Latest Podcast Trends

Few Listeners Express Issues with Objectionable Content Driven by Podcast Newcomers, Watchable Podcasts Are Growing in Popularity 20% of Weekly Podcast Listeners with Children Say They Frequently Listen to Podcasts with Their Kids NEW YORK, Nov. 29, 2022 (GLOBE NEWSWIRE) — Cumulus Media (NASDAQ: CMLS), in partnership with Signal Hill Insights, today released Cumulus Media and Signal Hill Insights’ Podcast Download – Fall 2022 Report, a comprehensive evaluation of the podcast audience. The ninth edition of the study that examines weekly podcast listeners is part of Cumulus Media’s commitment to share insights and research findings with the podcast community. A key finding uncovered in the Podcast Download Report is that podcast listeners have no problem listening to podcasts with language or content that might be considered objectionable...

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Salona Global Executes Binding Agreement to Acquire the Physical Medicine Assets of Biodex Medical Systems, Inc.

Salona Global Executes Binding Agreement to Acquire the Physical Medicine Assets of Biodex Medical Systems, Inc.

SAN DIEGO, Nov. 29, 2022 (GLOBE NEWSWIRE) — Salona Global Medical Device Corporation (“Salona Global,” “SGMD,” or the “Company”) (TSXV:SGMD) has executed a definitive asset purchase agreement (the “Asset Purchase Agreement”) to acquire the physical medicine assets (the “Acquired Assets”) of Biodex Medical Systems, Inc. (“Biodex”). As part of the acquisition, at the closing the parties will execute a two-year contract manufacturing agreement (the “Supply Agreement”) with Biodex, which together with the Acquired Assets are expected to generate $26 million annually. The trailing 12-month revenues for the Acquired Assets were $18 million with gross margins of approximately 30%. The Supply Agreement is expected to generate 15% gross margins. Between cash, assets on the balance sheet and its existing debt facility the Company has sufficient...

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