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Day: June 7, 2021

Basilea reports new prevalence data for EB1, a potential response-predictive biomarker for lisavanbulin in glioblastoma and other tumor types, at ASCO Annual Meeting

Basel, Switzerland, June 07, 2021 Basilea Pharmaceutica Ltd. (SIX: BSLN) announced today that data on the prevalence of end-binding protein 1 (EB1) in glioblastoma and other tumor types is being presented at the American Society of Clinical Oncology (ASCO) Annual Meeting that takes place online from June 4 to 8, 2021. EB1 plays a pivotal role in the regulation of microtubule dynamics during cell division and has been shown to interact with microtubule-targeting agents, such as lisavanbulin, inhibiting tumor growth.1 EB1 has been identified as a response-predictive biomarker for Basilea’s tumor checkpoint controller lisavanbulin in pre-clinical glioblastoma models.2 In the previously reported phase 1 portion of the ongoing phase 1/2 clinical study, long-lasting clinical benefit was observed in two patients with recurrent glioblastoma whose...

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Addex Starts Phase 2 Clinical Study of ADX71149 for Epilepsy

First patients enrolled into multi-center U.S. study Geneva, Switzerland, June 7, 2021 – Addex Therapeutics (SIX: ADXN and Nasdaq: ADXN), a clinical-stage pharmaceutical company pioneering allosteric modulation-based drug discovery and development, today announced that the first patients have been enrolled into a Phase 2 clinical study evaluating JNJ-40411813 (ADX71149) in patients with epilepsy. JNJ-40411813 (ADX71149) is a selective metabotropic glutamate type 2 (mGlu2) receptor positive allosteric modulator (PAM). The trial is being conducted in collaboration with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson. “Addex is anticipating multiple clinical study catalysts during 2021. The first, starting with this epilepsy study, illustrates the continued commitment of our long-time...

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PGS ASA: Deploys Two Vessels to Expand Coverage Offshore Canada

June 7, 2021: Oslo, Norway, PGS seismic vessel Ramform Titan has begun acquisition of the Cape Anguille program, in partnership with TGS. This program expands the PGS-TGS joint venture with another 10 000 square kilometers of GeoStreamer 3D coverage in Newfoundland’s prospective Orphan Basin. The survey covers existing lease blocks and open acreage. Acquisition is expected to complete mid-September 2021. PGS will deliver fast-track results in November 2021, and final imaging and interpretation products in Q1 2022. In addition to Ramform Titan, Ramform Atlas is currently steaming towards Canada where she will start another MultiClient campaign in the first half of June. PGS plans to keep the Ramform Atlas in Canada until mid-September 2021. Rune Olav Pedersen, President and CEO of PGS comments: “Canada remains a good investment for explorers...

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Nyxoah BETTER SLEEP Trial Reaches its Primary Endpoints

  REGULATED INFORMATION INSIDE INFORMATION Nyxoah BETTER SLEEP Trial Reaches its Primary Endpoints Mont-Saint-Guibert, Belgium – 7 June 2021, 7:00 am CET / 1:00 am ET – Nyxoah SA (Euronext Brussels: NYXH) (“Nyxoah” or the “Company”), a medical technology company focused on the development and commercialization of innovative solutions to treat Obstructive Sleep Apnea (OSA), today announced that the BETTER SLEEP trial reached its primary safety and performance endpoints. The BETTER SLEEP trial was designed to assess the long-term safety and performance of the Genio® bilateral hypoglossal nerve stimulation system (the “Genio® system”) in 42 adult OSA patients with and without Complete Concentric Collapse (CCC) of the soft palate. Top-line results from the BETTER SLEEP study showed: A statistically significant mean reduction in Apnea Hypopnea...

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Disclosure of received notification of Templeton Investment Counsel, Kabouter Management and Alychlo

Regulated informationNazareth (Belgium)/Rotterdam (The Netherlands), 7 June 2021 Disclosure of received notification of Templeton Investment Counsel, Kabouter Management and Alychlo Pursuant to the Belgian law of 2 May 2007 regarding the disclosure of major shareholdings in listed companies, Fagron received a notification of Templeton Investment Counsel, LLC, Kabouter Management, LLC, and Alychlo NV. Notification of Templeton Investment Counsel, LLCOn 1 June 2021, Fagron received a notification that the shareholding of Templeton Investment Counsel, LLC had crossed the disclosure threshold of 3% on 27 May 2021 as the result of the acquisition of voting securities or voting rights. The notification is made by a ‘person that notifies alone’. On 27 May 2021, Templeton Investment Counsel, LLC held a total of 2,188,281 voting rights (previous...

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argenx to regain global rights to cusatuzumab

Regulated Information/Inside InformationJune 7, 2021 Breda, the Netherlands – argenx SE (Euronext & Nasdaq: ARGX), a global immunology company committed to improving the lives of people suffering from severe autoimmune diseases and cancer, today announced it will regain worldwide rights to its anti-CD70 antibody cusatuzumab from Cilag GmbH International, one of the Janssen Pharmaceutical Companies of Johnson & Johnson. Interim data from the Phase 1b ELEVATE trial support continued development in acute myeloid leukemia (AML) and argenx plans to evaluate options to enable a path forward. “We have valued the productive collaboration with Janssen that has advanced our understanding of cusatuzumab and its role in AML biology. Together we have generated clinical and translational data that have optimized the dose of cusatuzumab...

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TGS and PGS Announce Cape Anguille 3D Survey Offshore East Canada

OSLO, Norway (7 June 2021) – TGS, a global provider of energy data and intelligence, in partnership with PGS, today announced that it has commenced acquisition of the Cape Anguille 3D program.  This program expands the TGS-PGS joint venture with an additional 10,000 square kilometers of 3D coverage offshore Newfoundland. The survey covers existing lease blocks and open acreage in the prospective Orphan Basin. The Orphan Basin has, among others, potential Cretaceous and Tertiary infill depocentres. The data acquired and processed will include Kirchhoff 3D PSTM volumes, and PGS’ Ramform Titan will perform the long offset acquisition, utilizing Geostreamer® technology.  Kristian Johansen, CEO at TGS, commented, “The TGS and PGS joint venture offshore East Canada has successfully and consistently provided the industry with the highest quality...

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Clean Power Announces Name Change to PowerTap Hydrogen Capital Corp.

VANCOUVER, British Columbia and IRVINE, Calif., June 07, 2021 (GLOBE NEWSWIRE) — Clean Power Capital Corp. (NEO: MOVE)(FWB: 2K6)(OTC: MOTNF) (“Clean Power” or the “Company” or “MOVE”) is pleased to announce that the Company will change its name to “PowerTap Hydrogen Capital Corp.”, effective June 14, 2021, in conjunction with its transition to a single purpose hydrogen fueling technology company, previously announced on June 1, 2021. The Company will continue to trade under the stock symbol “MOVE” on the NEO Exchange (“NEO”).  This name change emphasizes the Company’s transition to a single purpose company from an investment issuer, redeploying its assets and resources to be a single purpose hydrogen fueling technology company. The name change and the transition to a single...

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SouthGobi Announces Business Update

VANCOUVER, British Columbia, June 06, 2021 (GLOBE NEWSWIRE) — SouthGobi Resources Ltd. (TSX: SGQ, HK: 1878) (“SouthGobi” or the “Company”) hereby announces a voluntary business update. The purpose of this announcement is to inform the Company’s shareholders (“Shareholders”) and potential investors of the latest business development of the Company. In light of the resurgence of COVID-19 pandemic in Mongolia, there has been additional precautionary measures imposed by the Chinese authorities at the Ceke Port of Entry, including but not limited to, restricting the number of trucks for border crossing. This is expected to have an adverse effect on the volume of coal exports from Mongolia and may negatively impact the sales and cash flow of the Company. In order to preserve its working capital, the Company’s management has adjusted...

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