Month: April 2021

Seven abstracts accepted show the potential of HSC gene therapy to transform the treatment of multiple severe rare disorders First peer-reviewed presentation from company’s work in transduction enhancers showcases promise to improve manufacturing efficiency of lentiviral-based gene therapy BOSTON and LONDON, April 28, 2021 (GLOBE NEWSWIRE) — Orchard Therapeutics (Nasdaq: ORTX), a global gene therapy leader, today announced the acceptance of seven abstracts at the 24th Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT) taking place virtually from May 11-14. Accepted abstracts include clinical data from several of its hematopoietic stem cell (HSC) gene therapy programs, including: OTL-203, being investigated for the treatment of mucopolysaccharidosis type I (MPS-I), and OTL-101, being investigated for the...

CAMBRIDGE, Mass., April 28, 2021 (GLOBE NEWSWIRE) — Trillium Therapeutics Inc. (NASDAQ/TSX: TRIL), a clinical stage immuno-oncology company developing innovative therapies for the treatment of cancer, today announced that it has dosed the first multiple myeloma patient with TTI-622 (SIRPα-IgG4 Fc), an investigational checkpoint inhibitor of the innate immune system, in combination with the proteasome inhibitor carfilzomib and dexamethasone. TTI-622 is a fusion protein that is designed to block the inhibitory activity of CD47, a molecule that is overexpressed by a wide variety of tumors. CD47 binds to SIRPα on macrophages and delivers a “don’t eat me” signal that inhibits the ability of macrophages to engulf and destroy cancer cells. Preclinical studies have shown that TTI-622 exhibits anti-myeloma activity as a monotherapy that...

HIAB XS 099 HiProHIAB XS 099 HiProHIAB XS 099 HiPro on roadHIAB XS 099 HiPro on roadHIAB XS 099 HiPro operatorHIAB XS 099 HiPro operator HIAB XS 099 HiProCARGOTEC CORPORATION, PRESS RELEASE APRIL 28 2021 AT 1:45 PM EEST Hiab, part of Cargotec, will supply the leading UK hard landscaping manufacturer Marshalls with 108 new HIAB loader cranes equipped with the connected service HiConnect™ and ProCare™ Total Repair and Maintenance contracts for eight years. The order value of EUR 4.9 million were ordered and booked in Cargotec’s quarter 1 order intake of 2021. Marshalls is a complete external landscaping products business – from planning to engineering, to guidance and delivery. From the highlands of Scotland to England’s southern tip, they offer a three-day delivery promise,...

LONG ISLAND CITY, N.Y., April 28, 2021 (GLOBE NEWSWIRE) — Steven Madden, Ltd. (Nasdaq: SHOO), a leading designer and marketer of fashion-forward footwear, accessories and apparel for women, men and children, today announced financial results for the first quarter ended March 31, 2021. Amounts referred to as “Adjusted” exclude the items that are described under the heading “Non-GAAP Adjustments.” First Quarter 2021 ReviewRevenue increased 0.5% to $361.0 million compared to $359.2 million in the same period of 2020. Gross margin increased 130 basis points to 38.5% compared to 37.2% in the same period of 2020. Operating expenses as a percentage of revenue were 30.6% compared to 33.8% in the same period of 2020. Adjusted operating expenses as a percentage of revenue were 28.7% compared to 33.2% in the same period of 2020. Income...

Revenue of $392.0 million, which is within prior guidance range Operating income of $11.2 million and operating margin of 2.9% both show sequential improvement Net Income of $3.2 million or earnings per share of $0.06 Backlog of $1.5 billion up 57% YoY; outperforms normal sequential seasonality 2021 EPS outlook maintained at $0.75 per diluted share; range of $0.70 to $0.80LAFAYETTE, Ind., April 28, 2021 (GLOBE NEWSWIRE) — Wabash National Corporation (NYSE: WNC), the innovation leader of engineered solutions for the transportation, logistics and distribution industries, today reported results for the quarter ended March 31, 2021. Net sales for the first quarter 2021 of $392.0 million increased 1.3% versus the prior year quarter as the Company continued to scale its ability to serve strong customer demand. Consolidated gross profit...

Press Release Nokia ranked as number one in 5G patentsIndependent study by PA Consulting confirms Nokia’s leadership in 5G Standard Essential Patents The finding is the latest to rank Nokia number one for patents declared as essential for cellular standards, including 5G28 April 2021 Espoo, Finland – Nokia today announced that it has been ranked as number one in 5G patents in an independent study. The strength of Nokia’s industry leading 5G patent portfolio has once again been confirmed by an independent third party. In its study on Standard Essential Patents (published April 2021), independent analyst firm PA Consulting concluded that Nokia is number one for ownership of granted patents that the researchers found essential to 5G standards. This is the second time Nokia’s leadership in 5G Standard Essential Patents has been confirmed...

TORONTO, April 28, 2021 (GLOBE NEWSWIRE) — Sprott Inc. (“Sprott”) (NYSE/TSX: SII) announced today that Sprott Asset Management LP (“Sprott Asset Management”), a wholly-owned subsidiary of Sprott has entered into a definitive agreement with Uranium Participation Corporation (“UPC”) (TSX: U) pursuant to which UPC shareholders will become unitholders of the Sprott Physical Uranium Trust (the “Trust”), a newly-formed entity managed by Sprott Asset Management. UPC is the world’s largest publicly traded investment vehicle providing investors an opportunity to gain exposure to the price of uranium, outside of a traditional mining company, through holdings of physical uranium in the form of uranium oxide in concentrates (“U3O8“) and uranium hexafluoride (“UF6“). At the end of March 2021, UPC reported holding 16,269,658...