Month: September 2020

Athenex 的口服紫杉醇加上 encequidar 正在與 GSK 的 dostarlimab 進行併用治療，並將其納入 nerefivant 化療中公司將主持會議通話和網絡廣播，時間為今天上午 10:30 （東部時間）。三藩市和紐約水牛城, Sept. 09, 2020 (GLOBE NEWSWIRE) — Quantum Leap Healthcare Collaborative (Quantum Leap) 和 Athenex, Inc. (Nasdaq: ATNX) 宣佈推出兩項 I-SPY 2 試驗的新研究組，在新輔助化療環境下評估 Athenex 口服紫杉醇加上 Encequidar 的併合使用與 GSK 的 dostarlimab（一種試驗性抗體結合劑 PD-1）的療效。研究的目標是在第 2/3 階段評估口服紫杉醇加上 encequidar 與 dostarlimab +/- 碳水化合物，以及在 HER2+ 患者使用 trastuzumab 的安全性和療效，如有需要，隨後使用 doxorbicin 加上 cyclophosphamide 化療 (AC) 和切除乳房組織。主要目標是確定這個方案相對於僅使用標準新輔助化療，對於在進入試驗時建立的任何腫瘤子類別是否會增加病理完全反應 (pCR) 的機率，並確定預測隨後第 3 階段試驗取得成功的可能性。主要終點是根據 pCR 測量結果的客觀反應率。這項測量將在治療結束後及在殘留疾病病理評估期間進行。pCR 被定義為乳房中（在最終手術切除時）或在淋巴結中（沒有由蘇木精-伊紅染色 (H&E stain) 確定的侵入性腫瘤）沒有殘留侵入性腫瘤。次要終點包括安全性評估和取得其他有關反應的資訊，方法是透過在治療期間及之後磁力共振 (MRI) 測量體積變化，旨在計算在殘留疾病病理評估時的殘餘腫瘤量 (RCB) 變化。這個方案有幾個創新的組成部分，包括：(1) 評估將 PD-1 封鎖延伸至 HER2+；(2)...

The proposed agreement is intended to provide a supply of 200 million doses and an option to purchase additional 100 million doses, with deliveries starting by the end of 2020, subject to regulatory approvalThe vaccine supply for the EU would be produced by BioNTech’s manufacturing sites in Germany and Pfizer’s manufacturing site in BelgiumPfizer and BioNTech are on track to seek regulatory review of BNT162b2 as early as October 2020 and, if regulatory authorization or approval is obtained, currently plan to supply up to 100 million doses worldwide by the end of 2020 and approximately 1.3 billion doses by the end of 2021NEW YORK and MAINZ, Germany, Sept. 09, 2020 (GLOBE NEWSWIRE) — Pfizer (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today announced that they had concluded exploratory talks with the European Commission for a proposed...

Die geplante Vereinbarung umfasst die Lieferung von 200 Millionen Impfstoffdosen sowie eine Option zum Erwerb von zusätzlichen 100 Millionen Dosen; Lieferung soll Ende 2020 starten, vorbehaltlich der behördlichen ZulassungDie Impfstofflieferung für die EU sollen in BioNTechs Produktionsstätten in Deutschland sowie Pfizers Produktionsstätte in Belgien hergestellt werdenPfizer und BioNTech planen weiterhin, die behördliche Zulassung für BNT162b2 bereits im Oktober 2020 zu beantragen und, sollte die Genehmigung oder Zulassung erfolgen, weltweit bis zu 100 Millionen Impfstoffdosen bis Ende 2020 und rund 1,3 Milliarden Impfstoffdosen bis Ende 2021 herzustellenNEW YORK und MAINZ, Deutschland, Sept. 09, 2020 (GLOBE NEWSWIRE) — Pfizer Inc. (NYSE: PFE) und BioNTech SE (Nasdaq: BNTX) gaben heute den Abschluss erster Gespräche mit der Europäischen...

Singapore, Sept. 09, 2020 (GLOBE NEWSWIRE) — Moxian, Inc. (“Moxian” or the “Company”) (MOXC), an offline-to-online (O2O) social media services and Internet media marketing services provider, today announces that its proposed merger partner under the definitive agreement signed on August 27, Btab Group Inc, (“Btab”) is offering 10,000 online storefronts to 10,000 small businesses with no set up fee and complete fulfillment to small business owners around the world.Btab partners with manufacturers to supply multiple types of products and will hold fulfillment for fast shipping to the country of the entrepreneur. Btab has an extensive product line and network for entrepreneurs to choose from, with a unique profit sharing structure for the product resellers.The economic incentive given by Btab is to assist small business during these...

Paris, le 9 septembre 2020Après une succession d’évènements de nature à fragiliser l’opération d’acquisition de la société Tiffany & Co, le Conseil d’administration de LVMH s’est réuni pour étudier la situation de l’investissement projeté au regard de récents développements.Le Conseil a ainsi pris connaissance d’une lettre du Ministre de l’Europe et des Affaires Etrangères qui, en réaction à la menace de taxes sur les produits français formulée par les Etats-Unis, demande au groupe LVMH de différer l’acquisition de Tiffany au-delà du 6 janvier 2021. Le Conseil a également pris note de la demande de Tiffany de repousser le délai limite de réalisation de l’accord du 24 novembre 2020 au 31 décembre 2020.Compte tenu de ces éléments, et connaissance prise des premières analyses juridiques menées par les conseils et les équipes de LVMH,...

LAKE FOREST, Ill., Sept. 09, 2020 (GLOBE NEWSWIRE) — Assertio Holdings, Inc. (“Assertio” or the “Company”) (Nasdaq: ASRT), a commercial-stage pharmaceutical company, announced that the company will present at and participate in investor meetings at the Cantor Virtual Global Healthcare Conference. President, chief executive officer and director of Assertio, Todd Smith, will participate in the fireside chat with analyst Louise Chen on September 16, 2020 at 2:00 pm ET. The topics to be covered will be the status of the integration of Zyla Life Sciences, and the company’s business development strategy, financial results, current growth trends and milestones over the coming 12 months.The Cantor Virtual Global Healthcare Conference 2020 will take place September 15, 16 and 17, 2020. For those interested in learning more, please visit...

ATLANTA, Sept. 09, 2020 (GLOBE NEWSWIRE) — Secureworks® (NASDAQ:SCWX), a leader in software-driven security solutions, today announced it has signed a definitive agreement to acquire Delve.Delve intelligently prioritizes vulnerabilities at scale and in context as part of its automated vulnerability management platform. The company’s SaaS solution is powered by artificial intelligence (AI) and machine learning to provide customers with more accurate and actionable data about the highest risk vulnerabilities across their network, endpoints and cloud.The acquisition demonstrates Secureworks’ commitment to evolving its cloud-native Red Cloak™ Platform, and extending Threat Detection and Response (TDR) application with new integrations, analytics and user experience improvements.The Delve all-in-one solution, automating asset discovery,...

ATLANTA, 09 sept. 2020 (GLOBE NEWSWIRE) — Secureworks® (NASDAQ : SCWX), un chef de file en solutions de sécurité logicielle, a annoncé aujourd’hui la signature d’un accord définitif visant l’acquisition de Delve.Delve priorise intelligemment les vulnérabilités selon l’échelle et le contexte dans le cadre de sa plateforme automatisée de gestion des vulnérabilités. La solution SaaS de la société repose sur l’intelligence artificielle (IA) et l’apprentissage machine pour fournir aux clients des données plus précises et mieux exploitables sur les vulnérabilités à haut risque de leur réseau, de leurs terminaux et de leur nuage.Cette acquisition démontre l’engagement de Secureworks à faire évoluer sa plateforme en nuage Red Cloak™ et à développer son application de détection et de réponse aux menaces (TDR) avec de nouvelles intégrations,...

VIRGINIA BEACH, Va., Sept. 09, 2020 (GLOBE NEWSWIRE) — Armada Hoffler Properties, Inc. (NYSE: AHH) today announced it has entered into a joint venture with Terwilliger Pappas to develop Solis Gainesville in Gainesville, Georgia.Solis Gainesville will be a new 223-unit multifamily development strategically located in downtown Gainesville, Georgia, approximately one hour northeast of Atlanta. In addition to boutique hotel-inspired amenities, the $52 million project will feature public park and civic space connecting to an existing pedestrian bridge that provides direct walkable access to upscale retail, dining, greenway, performing arts, and cultural offerings as well as Gainesville City Hall and the historic Gainesville Square.The City of Gainesville is located in Northeast Georgia, approximately 50 miles northeast of Atlanta and...