Day: April 30, 2020

Athenex 宣佈 ASCO20 虛擬科學計劃將接受口服紫杉醇二期血管肉瘤研究

紐約州水牛城, April 30, 2020 (GLOBE NEWSWIRE) — Athenex, Inc. (NASDAQ: ATNX) 是一家全球生物製藥公司,致力於發現、開發和商業化用於治療癌症和相關病症的新型療法,今天宣佈其正在進行的口服紫杉醇和 encequidar(口服紫杉醇;前稱 Oraxol)用於治療血管肉瘤的二期研究摘要,已獲接受在 American Society of Clinical Oncology (美國臨床腫瘤學會,ASCO) 將於 2020 年 5 月 29 日至 5 月 31 日舉行的 ASCO20 虛擬科學計劃中的海報討論會上演講發表。演講詳情如下:標題: (摘要 11517) Oraxol 用於治療不可切除皮膚血管肉瘤的二期研究海報會議:肉瘤地點:ASCO 虛擬科學計劃這項二期研究是一項正在進行的單臂研究,評估皮膚血管肉瘤患者口服紫杉醇(205 mg/m2) 加口服 encequidar 每天一次,每週連續 3 天的活性、安全性和耐受性 (clinicaltrials.gov 標識碼:NCT03544567)。摘要標題目前載於 ASCO 會議資料庫,完整摘要預計於 2020 年 5 月 13 日下午 5:00 (美國東部夏令時間)。Orascovery 平台最初由 Hanmi Pharmaceuticals 開發,除了 Hanmi 保留了韓國的使用權外,它獨家授予 Athenex 全球所有主要地區的使用權。關於血管肉瘤血管肉瘤是一種軟組織肉瘤,其特徵在於快速增長、廣泛滲透及來自血液和淋巴管的間變性細胞。血管肉瘤出現在身體各個部位,包括皮膚、軟組織和內臟。血管肉瘤在診斷時經常轉移,具有自然病史並發局部復發、遠處轉移和總體生存率低。血管肉瘤沒有得到批准的治療,目前可用的治療方法的存活率有限。 然而,文獻中關於患者腫瘤反應的報導支持使用靜脈內紫杉醇治療血管肉瘤。關於 Athenex, Inc.創於 2003 年, Athenex,...

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Calithera Biosciences Announces Telaglenastat KEAPSAKE Trial in Progress Abstract Accepted for Presentation at ASCO20 Virtual Annual Meeting

SOUTH SAN FRANCISCO, Calif., April 30, 2020 (GLOBE NEWSWIRE) — Calithera Biosciences, Inc. (Nasdaq: CALA), a clinical stage biotechnology company focused on discovering and developing novel small-molecule drugs for the treatment of cancer and other life-threatening diseases, today announced that an abstract describing a Phase 2 study of telaglenastat, the company’s glutaminase inhibitor, will be presented at the American Society of Clinical Oncology 2020 (ASCO20) Virtual Annual Meeting.The KEAPSAKE study (NCT04265534) will explore telaglenastat versus placebo in combination with a standard-of-care regimen of immunotherapy and chemotherapy as first-line treatment for patients with non-small cell lung cancers (NSCLC) with KEAP1/NRF2 mutations. These mutations, which occur in an estimated 20 percent of NSCLC patients, are associated...

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Altra Industrial Motion Corp. Announces Second Quarter 2020 Dividend

BRAINTREE, Mass., April 30, 2020 (GLOBE NEWSWIRE) — Altra Industrial Motion Corp. (Nasdaq: AIMC), a leading global manufacturer and supplier of motion control, power transmission and automation products, today announced that its Board of Directors has approved the payment of a quarterly cash dividend of $0.04 per share for the second quarter of 2020. This dividend represents a reduction from the dividend of $0.17 per share declared in the first quarter of 2020. Reducing the dividend to this level is expected to provide the Company with additional financial flexibility by freeing up more than $30.0 million of cash on an annualized basis. The second quarter 2020 dividend is the thirty-third consecutive dividend in the Company’s history. The dividend will be paid on July 6, 2020 to shareholders of record as of the close of business...

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Sandy Spring Bancorp Declares Quarterly Dividend

OLNEY, Md., April 30, 2020 (GLOBE NEWSWIRE) — Sandy Spring Bancorp, Inc., (Nasdaq- SASR), the parent company of Sandy Spring Bank, announced that the board of directors declared a quarterly common stock dividend of $0.30 per share payable on May 20, 2020 to shareholders of record on May 13, 2020. This dividend is consistent with the previous linked quarter and the second quarter of 2019.About Sandy Spring Bancorp, Inc./Sandy Spring BankSandy Spring Bancorp, Inc., headquartered in Olney, Maryland, is the holding company for Sandy Spring Bank, a premier community bank in the Greater Washington, D.C. region. With over 55 locations, the bank offers a broad range of commercial and retail banking, mortgage, private banking, and trust services throughout Maryland, Northern Virginia, and Washington, D.C. Through its subsidiaries, Rembert...

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Exterran Corporation Provides Operational Update and First Quarter 2020 Earnings Release and Conference Call Schedule

HOUSTON, April 30, 2020 (GLOBE NEWSWIRE) — Exterran Corporation (NYSE: EXTN) (“Exterran” or the “Company”) today provided an operational update and its first quarter 2020 earnings release and conference call schedule. Andrew Way, Exterran’s President and Chief Executive Officer commented, “We are in unprecedented times, not only managing the COVID-19 uncertainties but responding to the weakened commodity price environment. First and foremost, we continue to monitor the impact of COVID-19 and are focused on the health and well-being of our employees and the communities where we work and serve. At Exterran, our tie to natural gas, solid contracted backlog, and strong balance sheet with no near-term maturities differentiates us relative to many within the energy industry, and solidifies our long-term confidence in our business. This...

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Allegiance Bancshares, Inc. Reports First Quarter 2020 Results

Promptly supported customers, employees and community with proactive response to the COVID-19 pandemicApproved more than 3,500 loans in excess of $640 million within the Small Business Administration Paycheck Protection Program under the Coronavirus Aid, Relief and Economic Security Act (CARES Act) through April 26, 2020 Surpassed $5 billion in assets, further bolstering market position as the largest community bank exclusively focused on the Houston region Net interest margin increased to 4.15% for the first quarter 2020 from 4.11% for the fourth quarter 2019 Declared quarterly dividend of $0.10 per share of common stockHOUSTON, April 30, 2020 (GLOBE NEWSWIRE) — Allegiance Bancshares, Inc. (NASDAQ: ABTX) (Allegiance), the holding company of Allegiance Bank (the “Bank”), today reported net income of $3.5 million and diluted earnings...

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ORBCOMM Announces First Quarter 2020 Results

– Total Revenues of $66.2 Million, In Line with Guidance –– Service and Product Gross Margins Increase Over Last Year –– Cash Flow from Operations of $8.2 Million –ROCHELLE PARK, N.J., April 30, 2020 (GLOBE NEWSWIRE) — ORBCOMM Inc. (NASDAQ: ORBC), a global provider of Machine-to-Machine (M2M) and Internet of Things (IoT) solutions, today announced financial results for the first quarter ended March 31, 2020.The following financial highlights are in thousands of dollars and unaudited.(1) Non-GAAP financial measure. See “Non-GAAP Financial Measures” for a reconciliation of GAAP to Non-GAAP financial measures included with the financial tables at the end of this release.“We’re pleased with our results in the first quarter despite facing a difficult environment,” said Marc Eisenberg, ORBCOMM’s Chief...

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Zentalis Pharmaceuticals Announces FDA Clearance of IND Application for ZN-d5 for the Treatment of Hematologic Malignancies

NEW YORK and SAN DIEGO, April 30, 2020 (GLOBE NEWSWIRE) — Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics targeting fundamental pathways of cancers, today announced that the U.S. Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ZN-d5, an oral selective inhibitor of B-cell lymphoma 2 (BCL-2) initially in development for the treatment of hematologic malignancies.“The acceptance of this IND, our fourth cleared in only five years, highlights the capability and efficiency of our Integrated Discovery Engine in developing novel oncology therapies,” commented Dr. Anthony Sun, Chairman and Chief Executive Officer at Zentalis Pharmaceuticals. “BCL-2 is as an important mediator...

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BeyondSpring Reports Fourth-Quarter and Full-Year 2019 Financial Results and Operational Update

– FDA Submission to Change the Primary Endpoint for Study 106 Phase 3 into an Industry First and Robust Clinical Measure to Evaluate Superiority in CIN –– Initiated NDA Rolling Submission for Plinabulin for CIN in China in Q1 2020 –– On Track to Report Interim Analysis of Study 106 Phase 3 in Q2 2020 to Evaluate Superiority in CIN and Submit NDA for CIN in the U.S. in H2 2020 –NEW YORK, April 30, 2020 (GLOBE NEWSWIRE) — BeyondSpring Inc. (the “Company” or “BeyondSpring”) (NASDAQ: BYSI), a global biopharmaceutical company focused on the development of innovative cancer therapies, announced today its financial results and provided an operational update for the three months and year ended December 31, 2019.“In 2019, BeyondSpring transitioned into a late-stage development company with clear paths toward...

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ConnectOne Bancorp, Inc. Reports First Quarter 2020 Results

ENGLEWOOD CLIFFS, N.J., April 30, 2020 (GLOBE NEWSWIRE) — ConnectOne Bancorp, Inc. (Nasdaq: CNOB) (the “Company” or “ConnectOne”), parent company of ConnectOne Bank (the “Bank”), today reported net income of $6.0 million for the first quarter of 2020 compared with $20.8 million for the fourth quarter of 2019 and $11.6 million for the first quarter of 2019.  Diluted earnings per share were $0.15 for the first quarter of 2019 compared with $0.59 earned in the fourth quarter of 2019 and $0.33 earned in the first quarter of 2019. The decrease in net income and diluted earnings per share from the fourth quarter of 2019 was primarily due to an increase in provision for loan losses of $15.5 million substantially due to the economic uncertainties caused by the COVID-19 pandemic.  On January 2, 2020, the acquisition of Bancorp of New Jersey...

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