Day: April 3, 2020

Des données de phase III concernant Dupixent® (dupilumab) montrent une amélioration significative de la dermatite atopique sévère chez les enfants âgés de 6 à 11 ansLes données détaillées qui seront présentées à la conférence Revolutionizing Atopic Dermatitis montrent que l’ajout de Dupixent à des corticoïdes topiques a amélioré la cicatrisation de la peau ; les symptômes globaux de la maladie se sont améliorés en moyenne d’environ 80 %.Les données confortent le profil de sécurité et de tolérance observé dans le cadre des essais menés chez des adultes et des adolescents atteints de dermatite atopique, notamment le taux numériquement inférieur d’infections cutanées comparativement au placebo.L’extension des indications de Dupixent à l’enfant âgé de 6 à 11 ans fait actuellement l’objet d’un examen prioritaire de la FDA, dont la décision...

Investors House Oyj                                                                          Lehdistötiedote 3.4.2020 klo 8.00INVESTORS HOUSE: MAALISKUUSSA DIGILOIKKA VUOKRA-ASUNTOIHINAsiakkaat ottivat ja vuokrasivat maaliskuussa asuntoja sähköisesti enemmän kuin koskaan aiemmin videoiden ja sähköisten toimintojen kautta. ”Vuokralaiset ja vuokranantajat ottivat kunnon digiloikan maaliskuun lopulla. Arvioni on, että maaliskuun loppupuolella 75% sopimuksista on tehty digitaalisen näytön perusteella. Vuokraus digi-kanavan kautta räjähti kerralla – pysytään kotona ja vuokrataan sähköisesti!” sanoo Kiinteistövarallisuudenhoidosta vastaava johtaja Marita Polvi-Lohikoski.Kiinteistöliiketoiminnan koko arvoketjussa toimivan Investors House-konsernin Kiinteistövarallisuudenhoito -yksikkö vuokrasi maaliskuussa yhteensä 348 asuntoa, 6 prosenttia...

SSH.COM provides mission-critical security to one of the largest banks in South-East AsiaHelsinki, Finland, and Hong Kong – April 3, 2020 – OCBC Bank, one of the largest banks in South-East Asia, has selected several products from SSH.COM, including Tectia® Client/Server and PrivX® to secure their mission-critical IT infrastructure.OCBC Bank is the longest established Singapore bank, formed in 1932 from the merger of three local banks, the oldest of which was founded in 1912. It is now the second-largest financial services group in Southeast Asia by assets and one of the world’s most highly-rated banks, with an Aa1 rating from Moody’s. Recognized for its financial strength and stability, OCBC Bank is consistently ranked among the World’s Top 50 Safest Banks by Global Finance and has been named Best Managed Bank in Singapore by The Asian...

SSH.COM tarjoaa liiketoimintakriittistä tietoturvaa  yhdelle Kaakkois-Aasian suurimmista pankeistaHelsinki – 3.4.2020 – OCBC Bank, yksi Kaakkois-Aasian suurimmista pankeista, on valinnut useita SSH.COM:in tuotteita turvaamaan pankin liiketoimintakriittistä IT-infrastruktuuria. Toimitukseen kuuluu mm. Tectia® Client/Server- ja PrivX®-tuotteita.OCBC Bank on Singaporen vanhin toimiva pankki, joka syntyi vuonna 1932 kolmen paikallisen pankin yhteenliittymänä. Vanhin näistä pankeista oli perustettu vuonna 1912. OCBC on nykyään taseeltaan Kaakkois-Aasian alueen toiseksi suurin finanssipalveluryhmä ja yksi maailman parhaiten luokitelluista pankeista, jolla on Moody’s:in Aa1-luokitus. OCBC Bank tunnetaan taloudellisesta vahvuudestaan ja vakavaraisuudesta ja se on säännöllisesti mukana Global Financen maailman viidenkymmenen turvallisimman pankin...

NOT FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR FOR DISSEMINATION IN THE UNITED STATESTORONTO, April 02, 2020 (GLOBE NEWSWIRE) — Hampton Bay Capital Inc. (the “Corporation” or “Hampton Bay”) (TSX-V: HPB.P) is pleased to announce that it has filed its filing statement dated March 30, 2020 in connection with it proposed business combination with Lendified Holdings Inc. (“Lendified”).  The filing statement is available under the Corporation’s profile at www.sedar.com.As previously announced on December 24, 2019 and January 20, 2020, Hampton Bay has entered into a letter of intent dated December 20, 2019, as amended on January 30, 2020 and February 14, 2020 (the “LOI”), with Lendified to effect an arm’s length transaction that will result in the reverse takeover of Hampton Bay by Lendified (the “Proposed Transaction”) to ultimately...

NEW YORK and SAN DIEGO, April 02, 2020 (GLOBE NEWSWIRE) — Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics targeting fundamental biological pathways of cancers, today announced the pricing of its initial public offering of 9,180,000 shares of common stock at a public offering price of $18.00 per share, for total gross proceeds of approximately $165.2 million, before deducting underwriting discounts and commissions and offering expenses payable by Zentalis. All of the common stock is being offered by Zentalis. The offering is expected to close on April 7, 2020, subject to customary closing conditions. In addition, Zentalis has granted the underwriters a 30-day option to purchase up to an additional 1,377,000 shares of its common...

HOUSTON, April 02, 2020 (GLOBE NEWSWIRE) — Kayne Anderson Midstream/Energy Fund, Inc. (the “Fund”) (NYSE: KMF) today provided a summary unaudited statement of assets and liabilities and announced its net asset value and asset coverage ratios under the Investment Company Act of 1940 (the “1940 Act”) as of March 31, 2020. As of March 31, 2020, the Fund’s net assets were $186 million and its net asset value per share was $3.93.  As of the same date, the Fund had $148 million of cash on its balance sheet, including cash it has received since month end for securities it has recently sold. It is the Fund’s intention to comply with all applicable 1940 Act leverage tests as well as the covenants on its debt agreements and of its preferred stock. The Fund plans to prudently use its cash balance to reduce leverage levels over the next month...

HOUSTON, April 02, 2020 (GLOBE NEWSWIRE) — Kayne Anderson MLP/Midstream Investment Company (the “Company”) (NYSE: KYN) today provided a summary unaudited statement of assets and liabilities and announced its net asset value and asset coverage ratios under the Investment Company Act of 1940 (the “1940 Act”) as of March 31, 2020.As of March 31, 2020, the Company’s net assets were $556 million, and its net asset value per share was $4.39. As of the same date, the Company had $560 million of cash on its balance sheet, including cash it has received since month end for securities it has recently sold. It is the Company’s intention to comply with all applicable 1940 Act leverage tests as well as the covenants on its debt agreements and of its preferred stock. The Company plans to prudently use its cash balance to reduce leverage levels...

圣地亚哥, 加利福尼亚洲, April 03, 2020 (GLOBE NEWSWIRE) — 美冠科今天宣布，通过与华盛顿大学CoMotion和Dana Farber癌症研究所达成的新协议，将战略性地扩大PDX模型库。这些协议将分别为肿瘤药物开发提供急需的前列腺癌和淋巴瘤模型。PDX模型是目前最具可译性的临床前体内模型，是临床前肿瘤药物发现和开发的首选模型。然而，某些PDX模型很难从特定的适应症（包括前列腺癌）中获得，而其他临床相关的突变在目前的PDX集合中没有充分的代表性。中美冠科与华盛顿大学CoMotion的合作将显著增加市场上可供使用的前列腺癌PDX模型的数量。增加了中美冠科已建立的前列腺癌PDX模型库，这组新的LuCaP PDX模型将提供广泛的临床相关模型，包括难以治疗的耐去势前列腺癌，对靶向药物如abiraterone和enzalutamide耐药的PDX模型，以及与疾病相关的包括Arv7雄激素受体表达谱。与Dana Farber癌症研究所的合作将转而为中美冠科的投资组合带来各种各样的淋巴瘤模型，包括T/NK、套细胞和滤泡性淋巴瘤，以及来自难治或复发患者的DLBCL。还包括具有共同药物靶点的模型，例如具有IDH1突变的脑癌PDX模型和具有靶向药物发现所必需的受体酪氨酸激酶改变的NSCLC-SCC-PDX。“通过这些令人振奋的协议，我们能够为那些急需更多模型的研究领域提供特性良好的PDX模型，”中美冠科研发部副总裁Davy Ouyang博士说。“中美冠科是PDX技术领域的全球领先者，我们的西方国家模型库将通过这些新增模型得到显著加强，从而使我们的全球客户群更容易获得最前沿的模型。”新的模型现在将在中美冠科的内部进行扩展，生物库化和特征化，然后将用于各种肿瘤学和免疫肿瘤学研究。这包括药效评估、小鼠临床试验、CAR-T细胞治疗评估、人源化和器官开发。关于中美冠科中美冠科是一家JSR生命科学公司，是全球性的药物发现和开发服务公司，为推进肿瘤、炎症和代谢疾病的研究提供转化平台。中美冠科拥有广泛的相关模型和预测工具，为客户供优质的临床候选药物。欲知详情，请浏览:https://www.crownbio.comhttps://www.jsrlifesciences.com关于华盛顿大学路透社将华盛顿大学（university...